Structure of PDB 7afn Chain J Binding Site BS01

Receptor Information
>7afn Chain J (length=99) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLI
SPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
Ligand information
>7afn Chain 1 (length=456) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaacc
uuaccuggucuugacauccacggaaguuuucagagaugagaaugugccuu
cgggaaccgugagacaggugcugcauggcugucgucagcucguguuguga
aauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcca
gcgguccggccgggaacucaaaggagacugccagugauaaacuggaggaa
gguggggaugacgucaagucaucauggcccuuacgaccagggcuacacac
gugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgga
ccucauaaagugcgucguaguccggauuggagucugcaacucgacuccau
gaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacgu
ucccgg
<<<.<<.<<<<<...<<<<<<<<<<......<<........>>.......
.<.<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<<..
..>>..>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....
>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<..
.<<<.....>>>.>....>>>>>>>.....<<<<<.....>>>>>.....
...>>>>.........>>>...>>>>>>>>>...>>>>>>>>..>>.>>>
>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>...
.>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>.
...>......>>>>>....<<<<<<<.........>>>>>>>......>>
...>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7afn A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Resolution3.86 Å
Binding residue
(original residue number in PDB)
R9 H15 R16 R37 P39 I40 P41 L42 P43 T44 R45 E47 T50 S54 P55 H56 V57 N58 K59 D60 R62 Q64 H70 R72
Binding residue
(residue number reindexed from 1)
R6 H12 R13 R34 P36 I37 P38 L39 P40 T41 R42 E44 T47 S51 P52 H53 V54 N55 K56 D57 R59 Q61 H67 R69
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0001072 transcription antitermination factor activity, RNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0031564 transcription antitermination
GO:0032784 regulation of DNA-templated transcription elongation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0008023 transcription elongation factor complex
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:7afn, PDBe:7afn, PDBj:7afn
PDBsum7afn
PubMed34088665
UniProtP0A7R5|RS10_ECOLI Small ribosomal subunit protein uS10 (Gene Name=rpsJ)

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