Structure of PDB 7af3 Chain J Binding Site BS01

Receptor Information
>7af3 Chain J (length=100) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVL
ISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
Ligand information
>7af3 Chain 1 (length=456) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaacc
uuaccuggucuugacauccacggaaguuuucagagaugagaaugugccuu
cgggaaccgugagacaggugcugcauggcugucgucagcucguguuguga
aauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcca
gcgguccggccgggaacucaaaggagacugccagugauaaacuggaggaa
gguggggaugacgucaagucaucauggcccuuacgaccagggcuacacac
gugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgga
ccucauaaagugcgucguaguccggauuggagucugcaacucgacuccau
gaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacgu
ucccgg
<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<...<<<<<<....>>>>>>....<<..
..>>..>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....
>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<<.
.<<<.....>>>>>....>>>>>>>.....<<<<<.....>>>>>.....
...>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>
>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>...
.>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>.
...>.....>>>>>>....<<<<<<<.........>>>>>>>......>>
...>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7af3 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		R7 R9 K11 H15 R37 G38 P39 I40 P41 L42 P43 T44 R45 T50 I53 S54 P55 H56 V57 N58 K59 A61 R62 Q64 R68 H70 L73
Binding residue
(residue number reindexed from 1)		R5 R7 K9 H13 R35 G36 P37 I38 P39 L40 P41 T42 R43 T48 I51 S52 P53 H54 V55 N56 K57 A59 R60 Q62 R66 H68 L71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0001072 transcription antitermination factor activity, RNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0031564 transcription antitermination
GO:0032784 regulation of DNA-templated transcription elongation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0008023 transcription elongation factor complex
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7af3, PDBe:7af3, PDBj:7af3
PDBsum7af3
PubMed34088665
UniProtP0A7R5|RS10_ECOLI Small ribosomal subunit protein uS10 (Gene Name=rpsJ)

[Back to BioLiP]