Structure of PDB 6rie Chain J Binding Site BS01

Receptor Information
>6rie Chain J (length=61) Species: 10245 (Vaccinia virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VFQLVCSTCGKDISHERYKLIIRKKSLKDVLVSVKNECCRLKLSTQIEPQ
RNLTVQPLLDI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6rie Chain J Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6rie Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		C7 C10 C39 C40
Binding residue
(residue number reindexed from 1)		C6 C9 C38 C39
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rie, PDBe:6rie, PDBj:6rie
PDBsum6rie
PubMed31835031
UniProtP68314|RP07_VACCA DNA-directed RNA polymerase 7 kDa subunit (Gene Name=OPG090)

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