Structure of PDB 6hc3 Chain J Binding Site BS01
Receptor Information
>6hc3 Chain J (length=191) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT
Ligand information
>6hc3 Chain K (length=22) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
taacaaaaaatttccaccaaac
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6hc3
DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
K51 K52 V54 L58 K62 R140 K146 K147 R157 Y162 Q179 L182 K186 Y211 R232 R233 T234
Binding residue
(residue number reindexed from 1)
K8 K9 V11 L15 K19 R97 K103 K104 R114 Y119 Q136 L139 K143 Y168 R189 R190 T191
Binding affinity
PDBbind-CN
: Kd=13.6nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6hc3
,
PDBe:6hc3
,
PDBj:6hc3
PDBsum
6hc3
PubMed
31114891
UniProt
Q00059
|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)
[
Back to BioLiP
]
