Structure of PDB 6awc Chain J Binding Site BS01

Receptor Information

>6awc Chain J (length=151) Species: 562 (Escherichia coli)

PRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLA
QRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAM
RWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAF
A

Ligand information

>6awc Chain A (length=1443)

aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacga
guggcggacgggugaguaaugucugggaaacugccugauggagggggaua
acuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagagg
gggaccuucgggccucuugccaucggaugugcccagaugggauuagcuag
uaggugggguaacggcucaccuaggcgacgaucccuagcuggucugagag
gaugaccagccacacuggaacugagacacgguccagacuccuacgggagg
cagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugcc
gcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagga
agggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaagc
accggcuaacuccgugccagcagccgcgguaauacggagggugcaagcgu
uaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaagucag
augugaaauccccgggcucaaccugggaacugcaucugauacuggcaagc
uugagucucguagagggggguagaauuccagguguagcggugaaaugcgu
agagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagacu
gacgcucaggugcgaaagcguggggagcaaacaggauuagauacccuggu
aguccacgccguaaacgaugucgacuuggagguugugcccuugaggcgug
gcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgcaa
gguuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcaug
ugguuuaauucgaugcaacgcgaagaaccuuaccuggucuugacauccac
ggaaguuuucagagaugagaaugugccuucgggaaccgugagacaggugc
ugcauggcugucgucagcucguguugugaaauguuggguuaagucccgca
acgagcgcaacccuuauccuuuguugccagcgguccggccgggaacucaa
aggagacugccagugauaaacuggaggaagguggggaugacgucaaguca
ucauggcccuuacgaccagggcuacacacgugcuacaauggcgcauacaa
agagaagcgaccucgcgagagcaagcggaccucauaaagugcgucguagu
ccggauuggagucugcaacucgacuccaugaagucggaaucgcuaguaau
cguggaucagaaugccacggugaauacguucccgggccuuguacacaccg
uaacaagguaaccguaggggaaccugcgguuggaucaccuccu

.......<<<<<.[.((((>>>>>.<<<<.<<<<<...<<<<<<......
<<<.<<<...<<..<<.<...<<.<<<<<.......>.>>>>..>>.>..
>>>>.......<<.......<<<<<<<..<<...<<<<<<<...<<....
.<<<<<......>>>>>......>>.......<<......>>....<<<<
<<..<<....>>>>>>>>.>>>>>>>..>>.>>>>>>><<<..<.<<<..
.<<<<<<.........>>>>>>.>>>....>.>>>..<<<<<<<<....>
>>...>>>>>.>>.<<<<<............>>>>>.<<<.<..>.>>>.
..>>>>>>.........<<...<<<<<<....>>>>.>>>>...>.>>>>
>...<<<<.......<<<....>>>......>>>>..<<.<<<<<.....
...<<<<<<<<.......>>>>>>>>..........>>>>>....>>.<<
<<<(((...<<<<<........))).........>>>>>>>>>>..>>>>
>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<
<<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>
...<<<<<<<<...<<<<<<<....<<<<<<<<.<.<<<......>>>..
...>>>>>>>>.>..........<<....>>.>>>>>>>..>>>.>>>>>
...>>>...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>..
.>>>>>>>>..........<<<<<<..<<<<<<.<<<<<.....>>>>>.
>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.......<<<....
>>>.....>>>..)))).].<<<<.<<<<<<<.<<..<<<<...<<<<<<
<<<<......<<........>>..........<<<<<<<......<<<<<
<<..<<<<<<......>>>>>>...<<....>>..>>>>>.>>.<<<.<<
<..<<<<<<.......<<<<<<<<......>>..<<<<......>>>>..
>>>>>>.....<<<<.<<<<<<<...<....<<.....>>..>....>>>
>>>>.....<<<<<.....>>>>>........>>>>.........>>>..
.>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<....
.<<<..<....<<......>>....>....>>>.....>>>>>>>.....
.<....<<<<<<<........>>>>>>>....>......>>>>.....<<
<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>......
.........<<<<<<<<<....>>>>>>>>>............

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6awc Structure of RNA polymerase bound to ribosomal 30S subunit.
• Resolution: 7.9 Å
• Binding residue (original residue number in PDB): P1 R2 R3 R4 V5 Q8 R9 N27 V31 D32 G33 K35 T37 I41 R91 R94 R101 D112 K113 S114 M115 R118
• Binding residue (residue number reindexed from 1): P1 R2 R3 R4 V5 Q8 R9 N27 V31 D32 G33 K35 T37 I41 R91 R94 R101 D112 K113 S114 M115 R118

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0015935 small ribosomal subunit

External links

• PDB: RCSB:6awc, PDBe:6awc, PDBj:6awc
• PDBsum: 6awc
• PubMed: 29027901
• UniProt: P02359|RS7_ECOLI Small ribosomal subunit protein uS7 (Gene Name=rpsG)