Structure of PDB 5zwo Chain J Binding Site BS01

Receptor Information
>5zwo Chain J (length=308) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLQKQQEEEELKRKLKQEEDEKDKRKLIEPNLELHEDKFLLDLSKFKIYY
DNNHGYEWWDTAYLVAHPLPEKIIKAYLTQHERKRLRRNRRKMAREAREI
KIKLGLLPKPEPKVKLSNMMSVFENDQNITDPTAWEKVVKDQVDLRKRKH
LEENERRHEDAIKRRKEAVNMNVEKPTVYHCKVFQFKNLQNPKIRFKLKM
NSKELSLKGLCLRIRDDGPGIIIVVGNEKSCKFYENLVMKRIKWNEDFEL
HTNTGDIKMDMHNNSISKTWEGYLQDCKFKGWFMKVCNDQDSLLRTLGQF
DSEHFYSP
Ligand information
>5zwo Chain F (length=99) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaaauuuuacuucguggacauuuggucaauuugaaacaauacag
aaucagcaguuccccugcauaaggaugaaccgucaaagagauuuguuuu
<<<<<<<<<.......>>>>>>>>>.........<<<......>>>....
.................................................
Receptor-Ligand Complex Structure
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PDB5zwo Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.9 Å
Binding residue
(original residue number in PDB)		P270 N276 S279 N312 R315 H316 P350 R353 F354 E362 R399 L408 H409 M442 K443
Binding residue
(residue number reindexed from 1)		P112 N118 S121 N154 R157 H158 P192 R195 F196 E204 R241 L250 H251 M284 K285
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005687 U4 snRNP
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwo, PDBe:5zwo, PDBj:5zwo
PDBsum5zwo
PubMed29794219
UniProtQ03338|PRP3_YEAST U4/U6 small nuclear ribonucleoprotein PRP3 (Gene Name=PRP3)

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