Structure of PDB 5mrw Chain J Binding Site BS01

Receptor Information
>5mrw Chain J (length=674) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAM
PGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKKTAFARK
LREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAI
TGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVE
GAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVAL
LVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDK
TGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAKQ
RFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEAN
GGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFA
QLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKL
IEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIM
CLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYG
LGGLLVPFIGIKVIDLLLTVCGLV
Ligand information
>5mrw Chain L (length=27) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MSAGVITGVLLVFLLLGYLVYALINAE
Receptor-Ligand Complex Structure
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PDB5mrw Crystal structure of the potassium-importing KdpFABC membrane complex.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		W31 R32 P34 F37 I38 K214 I226 I230 L233 L234 W240
Binding residue
(residue number reindexed from 1)		W23 R24 P26 F29 I30 K206 I218 I222 L225 L226 W232
Enzymatic activity
Catalytic site (original residue number in PDB) D307 D518 D522
Catalytic site (residue number reindexed from 1) D299 D510 D514
Enzyme Commision number 7.2.2.6: P-type K(+) transporter.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008556 P-type potassium transmembrane transporter activity
GO:0015662 P-type ion transporter activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031004 potassium ion-transporting ATPase complex
GO:1903103 potassium:proton antiporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5mrw, PDBe:5mrw, PDBj:5mrw
PDBsum5mrw
PubMed28636601
UniProtP03960|KDPB_ECOLI Potassium-transporting ATPase ATP-binding subunit (Gene Name=kdpB)

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