Structure of PDB 4hzc Chain J Binding Site BS01

Receptor Information

>4hzc Chain J (length=244) Species: 430066 (Brucella abortus S19) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VDPIWHSIRAEAEEATRNDPVLGAFLYATILNQPSLEEAVMHRIAERLGH
PDVSADILRQTFDTMLEANPEWSHVLRVDIQAVYDRDPAYSRFMDPVLYL
KGFHAIQTHRLAHWLYKQGRKDFAYYLQSRSSSIFQTDIHPAARLGSGLF
LDHATGLVVGETAVVEDNVSILHGVTLGGTGSSGDRHPKIRQGVLIGAGA
KILGNIQVGQCSKIAAGSVVLKSVPHNVTVAGVPARIIGETGCT

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

4hzc Chain J Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4hzc Crystal structure of serine acetyl transferase from Brucella abortus and its complex with coenzyme A.
Resolution	1.97 Å
Binding residue (original residue number in PDB)	H57 E61
Binding residue (residue number reindexed from 1)	H42 E46
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.3.1.30: serine O-acetyltransferase.

Gene Ontology

	Molecular Function
GO:0009001	serine O-acetyltransferase activity
GO:0016740	transferase activity
GO:0016746	acyltransferase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006535	cysteine biosynthetic process from serine
GO:0008652	amino acid biosynthetic process
GO:0019344	cysteine biosynthetic process

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4hzc, PDBe:4hzc, PDBj:4hzc
PDBsum	4hzc
PubMed	25058332
UniProt	A0A0F6AR69

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