Structure of PDB 4hnz Chain J Binding Site BS01

Receptor Information
>4hnz Chain J (length=174) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGST
ADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSA
EETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIAR
KAMRIATDIDVFSNEHWDVEVLEH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4hnz Chain J Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4hnz Structural and Biochemical Analyses of the Eukaryotic Heat Shock Locus V (HslV) from Trypanosoma brucei.
Resolution2.393 Å
Binding residue
(original residue number in PDB)		T157 D160 S163
Binding residue
(residue number reindexed from 1)		T157 D160 S163
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.25.2: HslU--HslV peptidase.
Gene Ontology
Molecular Function
GO:0004298 threonine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex
GO:0009376 HslUV protease complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4hnz, PDBe:4hnz, PDBj:4hnz
PDBsum4hnz
PubMed23818520
UniProtQ383Q5|HSLV_TRYB2 ATP-dependent protease subunit HslV (Gene Name=HslV)

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