Structure of PDB 3jbp Chain J Binding Site BS01

Receptor Information
>3jbp Chain J (length=188) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVQKRVLKSNPSDLEKEIAQCLLDIELSSSSDIKTDAKEIKLLSCDLIEV
EKLKKKTILIYIPYKIYTTYVRKIQRKLINELEKKTKKYVVLVAKRTILK
GKQKNKSFKIIPRSRTLTSVYDSILEDIVSPSEIIGKRISMKADGKRVFK
IMLDSKERQRDNIEEKLISFAAVYKKITRRDAVFSLPP
Ligand information
>3jbp Chain A (length=1608) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugaucuugccaguagucauaugcuugucucaaagauuaagcc
augcaagugaaaguauauauauauauauguagaaacugcgaacggcucau
uaaaacaguuauagucuacuugacauuuauaaggauaacuacggaaaagc
uguagcuaauacuugcauuauccuuuuggauaaguauuuguuagaaggaa
uuauaacaaagaaguaacacguaaaguguguaucaaucgaguuucugacc
uaucagcuuuugauguuaggguauuggccuaacauggcuaugacggguaa
cggggaauuagaguucgauuccggagagggagccugagaaauagcuacca
caucuaaggaaggcagcaggcgcguaaauuacccaauucuaaagaagaga
gguagugacaagaaauaacaaugcaagguuuguauuggaauggugggaau
uuaaaaccuucccagaguaacaauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuaaaauuguugcaguuaaaa
cgcucguaguugaauuucaaagaaucauucuuuuuaaaauccgauuuugu
uacuuugaguaaauuagaguguucaaagcaaacaguuaaagcauuguguu
ugaauacuauagcauggaauaacaaaauugaacaagcuaaaauuuuuugu
ucuuauuuuggcuuaguuacgauuaauaggaguagcuuggggacauucgu
auucagaugucagaggugaaauucuuagauuuucuggagacgaacaacug
cgaaagcauuugucuaaaauacuuccauuaaucaagaacgaaaguuaagg
gagugaagacgaucagauaccgucguaaucuuaaccauaaacuaugccga
cuagguguuggaugaagugcuuccuucaguaccuuaugagaaaucaaagu
cuuuggguucuggggcgaguauucgcgcaagcgagaaaguuaaaagaauu
gacggaagggcaccaccaggcguggagcuugcggcuuaauuugacucaac
acggggaaacucacuaguuuaagacauuggauggugaugcauggccguuu
uuaguucgugaaugauuugucugguuaauuccgauaacgaacgagaucuu
aaccugcuaauuagcggcgaguacacuguacuugcugcuucuuagaggaa
cauugugugucuaacacaaggaaguuuaaggcaacaacaggucugugaug
uccuuagaugaacuaggcugcacgcgugcuacacugauauauauaacgag
uaaaauaugcuugcauacuuuuccuccgccgaaaggcguagguaaucuuu
aucaauauauaucgugauggggauagauuauugcaauuauuaaucuugaa
cgaggaaugccuaguaagcaugauucaucagauugugcuaacuacguccc
ugcccuuuguacacaccgcccgucgcuccuaccgauugaaagauaugaug
aauuguuuggacaagaaaaauuuuuucuggaaaaaccguaaauccuaucu
uuuaaaggaaggagaagucguaacaagguuuccguaggugaaccugcgga
aggaucau
...<<<<<.[.((((>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<...<<<<<<..>>>>>>...>>.>>......<<...
.....<<<..<<..<<...<<<<........<<.....<<<<<<.....>
>>>>>......>>....<<<<<<....>>>>>>...<<<<<<<.<.....
.>.>>>>>>>.......<<<.....>>>....>>>>..>>>>..>>>.<<
<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>...
<<<<<<<<....>>>>...>>>>.>>.<<.<<<..........>>>.>>.
<.<<....>>.>...>>>>>>.........<<<....<<<.....>>>..
>>>..>....>>>.....<<<<<<<<<.>>>>>>>>>......<<<<<<.
........>>>>>>.........<<<<<((......<<<<.....<<..)
)>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<((....
.<.<<...<<<.<<....<<<<.<....>.>>>>..<<<......>>><<
<<<<.<<.......<<...<.......>.<<<<.......<<<.>>>>>>
>...>>......>>.>>..>>>>.....<<<<<.<<.<.<<<.<......
....>.>>>.>.>>.>>>.>>.>>....<<<<<<..<<..<<<<<..<<<
.<<<<<<.<...<<<......>>>......>.>>>>>>.>>>.......<
<....>>...>>>>>.>>.>>>.>>>...>>>...>>.>....<<<<<<.
..<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<
<.<<<<<<<<<<.<<<<..>>>>.>>>>>>>>>>...<<..))>>...>>
.....>>>.>>>.<<<.....<<<<<....>>>>>...>>>..)))).]<
<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<.......
.>>..........<<<<<<<....<<.>>...<<.<<<..<<<<<<<<<.
...<<<<<<<<<...>>>...<<<......>>>...>>>>>>....<<<<
<.<<<..<<...<<<<<<<<<<<<...>>>>>>>>>>>>...>>.>>>..
..<<<<<<.....>>>>>>.......>>>>>....>>>.>>>...>.>>>
>>>>.....>>>>>>>...>>.>>>>.>>>.....<<<<<<<<.....<<
...<.<<<<<..>>>>>.>...<<<.<<<<....>>>>.>>>....>>..
.....>>>>>>>>......<....<<<<<<..........>>>>>>....
>.....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<.<<<<<.<<<.
.<<.<<<<...<<.<<<<<.>>>.>>.>>...>>>>.>>..>>>.>>>>>
>.>...>>.>>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>
>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jbp Dynamical features of the Plasmodium falciparum ribosome during translation.
Resolution6.7 Å
Binding residue
(original residue number in PDB)		Y66 K67 R98 T99 K102 Q105 K108 S109 K111 I112 R115 S116 R117 T118 L119 T120 R149 R181 R182
Binding residue
(residue number reindexed from 1)		Y64 K65 R96 T97 K100 Q103 K106 S107 K109 I110 R113 S114 R115 T116 L117 T118 R147 R179 R180
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jbp, PDBe:3jbp, PDBj:3jbp
PDBsum3jbp
PubMed26432834
UniProtQ8IET7

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