Structure of PDB 8rd8 Chain IX Binding Site BS01

Receptor Information
>8rd8 Chain IX (length=142) Species: 45610 (Psychrobacter urativorans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKTLSAKPAEVTHDWFVVDADGKTLGRLATQIASRLRGKHKTNYTPHVDT
GDFIVVINAEKIAVTGKKAQDKKYYRHSGYPGGIKETNFTKLIAHKPEDV
LHKAVKGMLPKGPLGYAMIKKLKLYAGTDHPHEAQQPKELDI
Ligand information
>8rd8 Chain Z2 (length=2705) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaaguaaugaagcgcacaugguggaugccuuggcagucagaggcgaug
aaagacgugacagccugcgauaagcuucggggaggcggcaauauccugug
auccggagauuucugaauggggaaacccacuuaccauaagguagguaucu
ugaagaagcgaacgaggggaagugaaacaucucaguacccuuaggaaaag
acaucaaaugagauuccccaaguagcggcgagcgaacggggagaagccga
uuaaugcuaauguagaagaacagcgugggaaagcugaccguaguagguga
uaguccuguauucgaaacauuagcguuaacauauuaaguagggcgggaca
cgagaaauccugucugaagauggggggaccauccuccaaggcuaaauacu
ccugacugaccgauagugaaccaguaccgugagggaaaggcgaaaagaac
cccugugaggggagugaaauagaaccugaaaccgugugcguacaagcagu
aggagccucaauuuauuggggugacugcguaccuuuuguauaauggguca
gcgacuuauauucuguagcaagguuaaccguuuaggggagccguagggaa
accgagucuuaauagggcguaguugcaggguauagacccgaaaccgagug
aucuauccaugagcagguugaaagugccguaacaggcaccggaggaccga
acccacugucguugaaaagccaggggaugacuuguggauaggggugaaag
gcuaaucaaacucggugauagcugguucuccccgaaagcuauuuagguag
cgccucggacgaauaccauuggggguagagcacuguuucggcaccgaugc
aaacuccgaauaccgaugaguaauauccgggagacacacggcgggugcua
acguccgucguggagagggaaacaacccagaccgccagcuaaggccccaa
auuccuaguuaagugggaaacgaggugggaaggcauagacagcuaggagg
uuggcuuagaagcagccauccuuuaaagaaagcguaauagcucacuaguc
gagucggccugcgcggaagauguaacggggcucaaacuaggagccgaagc
ugcggauuugaaacuuguuuucaagugguaggggagcguuguguaagccu
gugaaggugugucguaaggcaugcuggagguaucacaagagcgaaugcug
acgugaguaacgauaaugcgagugaaaagcucgcacgccggaagaucaag
gguuccaguccaacguuaaucggggcugggugagucgaccccuaaggcga
ggccgaaaggcguagucgaugggaaauugguuaauauuccaauacuuguu
uauagugcgauggagggacggagaagguuaugucagccuggcguugguug
uccaggugaaaggauguaggcuuacaguuuaggcaaauccggacuguagg
cugagaucugauagcaaggaaguggcaaauaccaugcuuccaggaaaagc
uucuaagcgcuauaaacgaaucguacccuaaaccgacacaggugaucagg
uagagaauaccaaggcgcuugagagaacucugcugaaggaacuaggcaaa
augguaccguaacuucgggagaagguacgcuguugauggugauaggcucc
uugagcuuucgacagucgcagauaccaggcugcugcaacuguuuauuaaa
aacacagcacucugcaaacacgaaaguggacguauagggugugaugccug
cccggugcuggaagguuaauugaugggguuagcguaagcgaagcucuuga
ucgaagccccaguaaacggcggccguaacuauaacgguccuaagguagcg
aaauuccuugucagguaaguucugaccugcacgaauggcauaaugauggc
agcgcugucuccagcagagacucagugaaaucgaaaucgcagugaagaug
cuguguacccgcggcuagacggaaagaccccgugaaccuuuacuacagcu
uuacauugaacuuggguucuaacucagguauaacaauaccgaggacaaug
uaugguggguaguuugacuggggcggucuccuccuaaagaguaacggagg
aguacgaaggugcgcucagaacggucggaaaucguucauagaguauaaag
gcaaaagcgcgcuuaacugcgagacccacaagucgagcagguacgaaagu
aggucuuagugauccggugguucuguauggaagggccaucgcucaacgga
uaaaagguacucuggggauaacaggcugauaccgcccaagaguucauauc
gacggcgguguuuggcaccucgaugucggcucaucucauccuagggcuga
agcagguccuaaggguauggcuguucgccauuuaaagagguacgcgagcu
ggguuuagaacgucgugagacaguucggucccuaucuaccgugggcguug
gaaauuugagaggaucugcuccuaguacgagaggaccagaguggacgaac
cucugguguucggguugucacgccaguggcauugcccgguagcuacguuc
ggaugggauaaccgcugaaagcaucuaagcgggaagcccaccucaagauu
agauuucccuaaagagccguugaagacuacgacguugauaggcagggugu
ggaagugcagcgaugcauguagcuaaccuguacuaauugcucguuuggcu
ugacc
<<<<<<<......<<<<<<<<<<<.....[[.<<<<<<<<<<[[<<....
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.>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<<
<.>>>>.>>...<<<<<<.....<<....>>......>>>>>.>......
...<<....>>..<<<<<<.....<<.....>>....>>>>>>..((...
<<<<<<<<<<<<<.<<<...<<<<........>>>>((......<<<...
..))>>>...>>>...>>>>>>>>>>>>>...........<<<<<<<<..
.......>>>>>>>>......<<<<<..<<<<>>>>>...))......]]
.>>>>>>>.>>>..............<<....>>....]].........<
<<<.....>>>>..................>>>>>>>>>>>.......<<
<<..<<<<<<<....>>>>>>>..>>>>...<............>.<<<<
<<....<<<<<<<<<<<<<..<<<...<<.....>>...>>>...<<...
.>>..<<<<.....>>>>...>>>>>>>>>>>>>..<<.<...<<<<<<.
....<<<<<<<<<..<<<<....<<<<<......>>>>>..>...>>>..
.<<<.<<<.<........>.>>>>>>....>>>>>>>>>...<<<.....
>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>
>.<<<<<<<....<<<<<<<<<.....<<<...<<<.<<<<..>>>>.>>
>..>>.>.....>>>>>>.>>>...>>>>>>.>...<<<<<<<<<<....
..>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((..
...<<<<<<...........<<..<<<<<..<<........<<<<<.<<<
..<<<<.......>>>>..>>>........<<<......>>>..>>>>>.
...>>..>>>>>.>>...........)))......>>>>>>.>>>...>>
>>>>><<<<<<<<.....>>>>>>>>....>>>>>>..<<<<<...<<<.
.....<<<<<<<<....>>>>>>>>...>>>..>>>>>........>>>>
>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<
<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<...<<<..
.<<<....>>>...>>>...>>>..<<<<<........>>>>>))<<<<<
<<<<<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<...((((..
.>>>>>>....<<<<...<<<<.<<<<<<..<<.....>>.>>>>>>.>>
>>...>>>>.............>>>>>...>>>...>>>>.........>
>>>...>>>>>>>>>>>>>.>>>..>>.....<<......>>>>>>>.<<
<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<............
...<<<<<...............>>>>><<<<<<<<.<<<...<<<..>>
>...>>>.>>>>>>>>............<<<<<<<<<..<<<........
.>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<
<<..<<<<<<<..<<<<...<...<<<<<..<<....>>...>>>>>.>.
....>>>>>>>>>..>>>>><<<<<<.......>>>>>>........<..
.........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>
>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<........
>>>>>..<<<<<<<.<<<<.[[......<<<<.[[<<<<..<<<<<.<<<
.<<<<<.<<<<<..>>>>>...<<<.<<<<<....>>>>>>>>....>>>
>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>
>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.[.(((
>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>
>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>.........
....>>>>..]]>>>>.......<<<<...<<<<<<...<<.......>>
...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<..
....>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>...>>>
.>>....<<<<<<<....>>>.>>>>....]]..>>>>>>>>>>>....<
<<<<<<...<<<<..<<<<<<.................>>>>>>.<<<<<
...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>...>>>>.>>>>
>...<<<....<<<<<...........>>>>>....>>>.>>>>......
.>>>>>>>.....<<<<<<<<<.......>>>>>....<<<<<<<<..<<
....<<<<<....>>>>>...>>...>>>>>.>>>...>>>>.....>>>
>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rd8 A new family of bacterial ribosome hibernation factors
Resolution2.62 Å
Binding residue
(original residue number in PDB)		K2 T3 S5 K7 P8 W15 T24 G26 R27 T30 R37 K39 P46 H47 F53 T65 K67 K68 K72 Y75 R76 H77 S78 Y80 P81 G82 I84 H95 K96 A104 G107 M108 K111 P113 L114 Y116 H132 A134 Q135
Binding residue
(residue number reindexed from 1)		K2 T3 S5 K7 P8 W15 T24 G26 R27 T30 R37 K39 P46 H47 F53 T65 K67 K68 K72 Y75 R76 H77 S78 Y80 P81 G82 I84 H95 K96 A104 G107 M108 K111 P113 L114 Y116 H132 A134 Q135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8rd8, PDBe:8rd8, PDBj:8rd8
PDBsum8rd8
PubMed38355796
UniProtA0A0M4TBP4

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