Structure of PDB 8ow1 Chain II Binding Site BS01

Receptor Information
>8ow1 Chain II (length=704) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLILDDIILSLTNANERTPPQALKTTLSLLYEKSKQYGLSSPQLQALVR
LLCETSIIDTVTKVYIVENCFLPDGYLTKELLLEIINHLGTPTVFSRYRI
QTPPVLQSALCKWLVHVYFLFPVHSEREHNISSSIWLHLWQFSFLQKWIT
PLVIWQATTPVDVKPWKLSIIKRCAMHPGYRDAPGSATLILQRFQCLVGA
SSQITESIITINCNRKTLKSHRNLKLDAHFLSILKRILSRAHPANFPADT
VQNTIDMYLSEIHQLGADDSTVSLWDVTSLEQLAQNWPQLHIPNDVDYMM
KPRKVMSRDSLKHLYSSIILIKNSRDESSSPYEWCIWQLKRCFAHQIETP
QEVIPIIISVSSMDNKLSSRIIQTFCNLKYLKLDELTLKKVCGGILPLWK
PELISGTREFFVKFMASIFMWSTRDGNNCTFSETCFYVLQMITNWVLDDK
LIALGLTLLHDMQSLLTLDKIFNNATSNRFSTMAFISSLDILTQLSKQTK
SDYAIQYLIVGPDIMNKVFSSDDPLLLSAACRYLVATKNKLMQYPSTNKF
VRMQNQYIMDLTNYLYRNKVLSSKSLFGVSPDFFKQILENLYIPTADFKN
AKFFTITGIPALSYICIIILRRLETAENTKIKFTSGIINEETFNNFFRVH
HDEIGQHGWIKGVNNIHDLRVKILMHLSNTANPYRDIAAFLFTYLKSLSK
YSVQ
Ligand information
>8ow1 Chain D (length=153) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ataagtcacatggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaatattagtgta
tttgatttccgaaagttaaaaaagaaatagtaagaaatatatatttcatt
gaa
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ow1 Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		N214 R215 K216 K219
Binding residue
(residue number reindexed from 1)		N214 R215 K216 K219
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006270 DNA replication initiation
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0034087 establishment of mitotic sister chromatid cohesion
GO:0051301 cell division
GO:0051321 meiotic cell cycle
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ow1, PDBe:8ow1, PDBj:8ow1
PDBsum8ow1
PubMed37506202
UniProtQ12748|CENPI_YEAST Inner kinetochore subunit CTF3 (Gene Name=CTF3)

[Back to BioLiP]