Structure of PDB 7uck Chain II Binding Site BS01

Receptor Information
>7uck Chain II (length=203) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGG
NKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCI
VLIDSTPYRQWYESHYALPLGRKKLTPEEEEILNKKRSKKIQKKYDERKK
NAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKA
RKG
Ligand information
>7uck Chain 5 (length=3546) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggaaau
guggcguacggaagacccacuccccggcgccggggggcccaaguccuucu
gaucgaggcccagcccguggacggugugaggccgguagcggcccccggcg
cgccgggcccgggucuucccggagucggguugcuugggaaugcagcccaa
agcgggugguaaacuccaucuaaggcuaaauaccggcacgagaccgauag
ucaacaaguaccguaagggaaaguugaaaagaacuuugaagagagaguuc
aagagggcgugaaaccguuaagagguaaacgggugggguccgcgcagucc
gcccggaggauucaacccggcggccgguccggccgugccggcggggcgga
ucucccgcucccgucggcgggggaccgccccccggccggcgaccggccgc
cgccgggcgcauuuccaccgcggcggugcgccgcgaccggcuccgggacg
gcugggaaggccccggcggggaagguggcccgggggccccggguguuaca
gccccgccccggcagcagcagcucgccgaaucccggggccgagggagcga
gacccgugccgccgcgcucuccccccugggggggccgggccaccccuccc
acggcgcgaccgcuggggcggacuguccagugcgccccgggcgggucgcg
ccgucgggcccgggggccacggcgucccccgcgagcgcacggggucggcg
gcgaugucggcuacccacccgacccgucuugaaacacggaccaaggaguc
uaacacgugcgcgagucgggggcuacgaaagccgccguggcgcaaugaag
gugaaggccggcggcgccgccggccgaggugggaucccgaggccuuccag
uccgccgagggcgcaccaccggcccgucucgcccgccgcgccggggaggu
ggagcacgagcgcacguguuaggacccgaaagauggugaacuaugccugg
gcagggcgaagccagaggaaacucugguggagguccguagcgguccugac
gugcgaaucggucguccgaccuggguauaggggcgaaagacuaaucgaac
caucuaguagcugguucccuccaaaguuucccucaggauagcuggcgcuc
uccgcaguuuuauccgguaaagcgaaugauuagaggucuuggggccgaaa
cgaucucaaccuauucucaaacuuuaaauggguaagaagcccggcucgcu
gguguggagccgggcguggaaugcgagugccuagugggccacuuuuggua
agcagaacuggcgcugcgggaugaaccgaacgccggguuaaggcgcccga
ugccgacgcucaucagaccccagaaaagguguugguugauauagacagca
ggaugguggccauggaagucggaauccgcuaaggaguguguaacaacuca
ccugccgaaucaacuagcccugaaaauggauggcgcuggagcgucgggcc
cauacccggccgucgcuggcagucggcagagcgagaaagagaguggcgcg
gacgcuacgccgcgacgaguaggagggccgcugcggugagccuugaagcc
uagggcgcgggcccggguggagccgccgcaggugcagaucuuggugguag
uagcaaauauucaaacgagaacuuugaaggccgaaguggagaaggguucc
augugaacagcaguugaacaugggucagucgguccugagagaugggcgag
cgccguuccgaagggacgggcgauggccuccguugcccucagccgaucga
aagggagucggguucagauccccgaauccggaguggcggagaugggcgcc
gcgaggcguccagugcgguaacgcgaccgaucccggagaagccggcggga
gccccggggagaguucucuuuucuuugugaagggcagggcgcccuggaau
ggguucgccccgagagaggggcccgugccuuggaaagcgucgcgguuccg
gcggcguccggugagcucucgcuggcccuugaaaauccgggggagagggu
guaaaucucgcgccgggccguacccauauccgcagcaggucuccaaggug
aacagccucuggcauguuggaacaauguagguaagggaagucggcaagcc
ggauccguaacuucgggauaaggauuggcucuaagggcuggcagccgacu
uagaacuggugcggaccaggggaauccgacuguuuaauuaaaacaaagca
ucgcgaaggcccgcggcggguguugacgcgaugugauuucugcccagugc
ucugaaugucaaagugaagaaauucaaugaagcgcggguaaacggcggga
guaacuaugacucucuuaagguagccaaaugccucgucaucuaauuagug
acgcgcaugaauggaugaacgagauucccacugucccuaccuacuaucca
gcgaaaccacagccaagggaacgggcuuggcggaaucagcggggaaagaa
gacccuguugagcuugacucuagucuggcacggugaagagacaugaucgu
uuuuucacugacccggugaggcgggggggcgagccgggcucucgcuucug
gcgccaagcgcccggccggccgggcgcgacccgcuccggggacagugcca
gguggggaguuugacuggggcgguacaccugucaaacgguaacgcaggug
uccuaaggcgagcucagggaggacagaaaccucccguggagcagaagggc
aaaagcucgcuugaucuugauuuucaguacgaauacagaccgugaaagcg
gggccucacgauccuucugaccuuuuggguuuuaagcaggaggugucaga
aaaguuaccacagggauaacuggcuuguggcggccaagcguucauagcga
cgucgcuuuuugauccuucgaugucggcucuuccuaucauugugaagcag
aauucaccaagcguuggauuguucacccacuaauagggaacgugagcugg
guuuagaccgucgugagacagguuaguuuuacccuacugaugauguguug
uugccaugguaauccugcucaguacgagaggaaccgcagguucagacauu
ugguguaugugcuuggcugaggagccaauggggcgaagcuaccaucugug
ggauuaugacugaacgccucuaagucagaaucccgcccaggcggaacgau
agcgccggagccucgguuggccucggauagccggucccccgccggggucc
ggugcggagagcccuucgucccgggaaacggggcggccggaaagggggcc
gcccucucgcccgucacgcaccgcacguucguggggaaccuggcgcuaaa
ccauucguagacgaccugcuucugggucgggguuucguacguagcagagc
agcugcugcgaucuauugaaagucagcccucgacacaaggguuugu
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....
>>>>>>..[[[..<<<<<...<<<<<<<<<<.....>>>>>>.>>>>...
..>>>>>..<<<<<<<<<....<<<<<<<<..<<<<<<<<....<<<<..
....>>>>.....((......<<<.....))>>>...>.>>>>>>>...>
>>>>>>>...>>>>>>>>>.......<<<<<<<........>>>>>>>..
...(((((..<<<<<<)))))..]]]........................
..........<<....>>...............<<<<....>>>>.....
.............................<<<<<<<<..<<<.<<...<<
<<<<<<.<<<.....<<<<<<<<<....<<<<<<<.<<<<<.<<<<<<<.
<<<<<<<<<......>>>>>>>>>>>>>>>>>>>>>>>>>...>>>..>>
>>>>>>>......>>>.>>>.>>>>>...<<<<<<<<<<<<<<<<<<<<<
<<...<<..<<<..<<<<<<<......<<<<<<<<.>>>>>>>>......
.>>>>>>>..>>>.........>>>>>>..>>>>>>>>>>>.....<<..
...{.>>......<<<<<<.<<<<<<..>>>>>>.<<<<<<..<<<.<<<
<<<<<<<<<<<<<<<<<<<<.<<<<..>>>>.>>>>>>.>>>.>>>>>>>
>>>>.>>>...>>>>>>>.>>...........>>>>>>.....>>>.>>>
>>...>>>>>...>>>>>>>>..<<<<........>>>><<<<<<....<
<<<<<<<<<<<<..<<<...<<<<.....>>>>.....>>>...<<....
>>...<<<<<<<<....>>>>>>>>..<<<<<...<<<..<<<...(((.
[[.>>>..>>>....>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>
>>.>>....>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<
<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<.
.......>>>>.>>>....>>>>>>>>>...<<.......>>......>>
>>>>......>.>>..<<<<<<....<.<<<....>>>.><<.<<<<<<<
...<<<.<<<<<<<<<...<<<....<<<..<.<<<..<<<<.<......
...>.>>>>>>>.>..>>>..>.>>...>>>>>>>...<<<<<<<<<.<.
.....>>>>>>>>>>....>>>>>>>>>>>>..>>..<<<<.<<<<<...
..>>>>>.>>>>....<<<......>>>...<<<<<<<...<<<(((...
....<<<<<.....<<..........<<<.<<<<<<<<<<.......<<<
<<.<<.....................>>.........<<......>>...
>>>>>...>>>>>>>>>>>>>..........))).>>...>>>>>..>>>
...>>>>>>><<<<<<.<<<........}...........]].)))....
........>>>>>>>>>....>>>>>>.<.<<<<<<<<.<<......<<<
<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<...
..<<.....<<<<<<.......>>>>>>.<<<.....<<<<<.<<...<<
<<<<...<<.....>>.>>>>>>....((<<<<<<...<<....<<<...
.>>>..........<<.<<<<<<<<<...>>>>>>>>>>>......>>..
..>>>..<<<<<........>>>>>))<<<<....<<<<<..<<<<<<<<
....>>>>>>>>..<<<....>>>...<..<<<<<<<...<<<<<<<<<<
<<<<<<<<<<<<<..{{{..>>>>>>....<<<<<.<<<<.<<<<.....
<<<.....>>>.....>>>>>>>>..>>>>>.....<<<<<<<.......
>>>>>>>>>>>.>.>>>>>>>>>>>>.........>>>>>>>..>.....
.....>>.>>>.>>>>.>>>..>>.....<<......>>>>>>>.<<<<.
....>>>>..>>>....<<<<.....<<<<<<<.<<.........<....
.<<<<<....<<..>>.....>>>>><<.<<<<<<<<<<<.>>>>>..>>
>>>>.>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<
<<.....<<.....<<<<....>>>>.....>>..>>>>..>>>>><<<<
<<.......>>>>>>........<...........<<<<<.......>>>
>>.....>.....>>....>>.>>>>>>>..>..>>.>>>>>>>..>>>>
>>....>>....<<<<<........>>>>>....[[[[[..{{{.{{...
...[[[[.{{[[[[..<<<<<.<<<<<<<<<.<<<<<<<<<<......>>
>>>>>>>>...<<<<<.....<<<<..<<.<.<<<>>.>>.>>.......
.......<<<<<<<<<..>>>>>>>>>..>>>>..>>>>>....>>>>>>
>>>..>>>>>...<<<.....>>>..<<<<<<...........>>>>>>.
.<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.[.(((>>
....>>>>>>>...<<<..<<<<.......>>>>..>>>.<<<....>>>
.>>)))]......((((((..(((..>>>>>>.)))))))))........
..]]]]..}}]]]].......<<.<.<.<<<<<<...<<.......>>..
.>>>>>>...>>.>.>.......<<<<<.<<<<<<..<.<.<<<<<....
..>>>>>...>.>.<<<.........>>>.....>>>>>..>...>>>.>
>....<<<<<<<....>>>.>>>>....}}..}}}.]]]]].....<<<<
<<.<..<<<..<.<<<<<.................>>>>>.><<<<....
<<<<....<<.<<<<<<<}}}.>>>>>..>>.>>...>>>>...>>>><<
<<<...<<<<<...........>>>>>...>>>>>.>>>...>.>>>>>>
.<<<<<<<..<<<<....<<<........<<<<<..<<<<<.>>>>>.>>
>>>.......>>>...<<<..<<<<....<<<<<<<<<........>>>>
>>.>>>...>>>>..>>>..............>>>>..>>.>>>>>.<<<
<<.<.............>....<<.<<<<<<<.<<.....<<<<.<..<<
<<<.>>>>>..>>>>>....>>....>>>>.>>>.>>..>>>>>..
Receptor-Ligand Complex Structure
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PDB7uck Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
R92 R205
Binding residue
(residue number reindexed from 1)
R91 R201
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7uck, PDBe:7uck, PDBj:7uck
PDBsum7uck
PubMed35679869
UniProtG1TJW1|RS8_RABIT Small ribosomal subunit protein eS8 (Gene Name=RPS8)

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