Structure of PDB 7pub Chain IA Binding Site BS01

Receptor Information
>7pub Chain IA (length=693) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSQSSRGQPGLQWQEGVVDPRYSSSGNMRRFNPDTVAHYVKATIQNDRRE
MGLGEVYDWHEFAKDAVYIPTRSGPLWVGSDDPRCAKFMRRRSKMQKTPQ
QKARPKPGPDPAKALEDHPLREYFTTATNLRDPLSTANNLHRAGLIREYD
IKYTAAKVRYVPRPPVVSIMGHVDHGKTTLLDYLRKTNVASQEAGGITQN
VGAFQVKTLGDTLVTFIDTPGHAAFTTMREVGATANDLIVLVVSAVDGVQ
PQTKEVIELAHKSGIPFVVACTKIDRQPRVENVKQQLRDCNVELEEDGGD
TQFVPVCARDGRGVPELLEAIALQAELCEISTPKPSRCEVTVIETNGVNT
TTEVAGIVRCGKVRAGQVLVAGMTYAVVRKVLDEHGQIIQEAGPSQPVVL
HGFRVHPKPGSILLQVSSESHAQKFYHFMKEVYQAEGRREDYLQLLNQEQ
HGMLYARKPDNNLVRTYSTQAFVLSCKAATFGMLQALMKSIYEIPRLEGI
STEIKVTEVGGLRDYDVALIGSSGQPGCILLYGGCKDTNTLDVPNHVTVI
RFNVLYHGLEALKETLVGALPKITKIRVTAEAECLQVFRASAGGMRVTKG
TIIAAHLTFRVCRKRVVVYEGQIKELRRFKELVPSVELGLECGVIMQDEF
QFRTGDILQQYETYEEPRDVAEEYQKAELREKIMRDTAAAEAL
Ligand information
>7pub Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaagugcug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
aaaaauauauuuuuuuuuuuu
....................<<<.......<<<<<<............<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
..................................................
.................<<<.....<<<<<.....<<....>>.......
>>>>>>>>....>>.>>>>...............................
..................................................
..............................>>>....<............
.<<<<<............................................
..................................................
.....................>>>>>..................>.....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pub Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		R45 Q47 R60 T110 R111 S112 G113 K126 R129 R130 K133 Q140 A142 P144 K145 Y494 K497 P498
Binding residue
(residue number reindexed from 1)		R6 Q8 R21 T71 R72 S73 G74 K87 R90 R91 K94 Q101 A103 P105 K106 Y455 K458 P459
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008135 translation factor activity, RNA binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pub, PDBe:7pub, PDBj:7pub
PDBsum7pub
PubMed35042777
UniProtQ57WE3

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