Structure of PDB 7pua Chain IA Binding Site BS01

Receptor Information
>7pua Chain IA (length=704) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSQSSRGQPGLQWQEGVVDPRYSSSGNMRRFNPDTVAHYVKATIQNDRRE
MGLGEVYDWHEFAKDAVYIPTRSGPLWVGSDDPRCAKFMRRRSKMQKTPQ
QKARPKPGPDPAKALEDHPLREYFTTATNLRDPLSTANNLHRAGLIREYD
IKYTAAKVRYVPRPPVVSIMGHVDHGKTTLLDYLRKTNVASQEAGGITQN
VGAFQVKTLGDTLVTFIDTPGHAAFTTMREVGATANDLIVLVVSAVDGVQ
PQTKEVIELAHKSGIPFVVACTKIDRQPRVENVKQQLRDCNVELEEDGGD
TQFVPVCARDGRGVPELLEAIALQAELCEISTPKPSRCEVTVIETNGVNT
TTEVAGIVRCGKVRAGQVLVAGMTYAVVRKVLDEHGQIIQEAGPSQPVVL
HGFRVHPKPGSILLQVSSESHAQKFYHFMKEVYQAEGRREDYLQLLNQEQ
HGMLYARKPDNNLVRTYSTQAFVLSCKAATFGMLQALMKSIYEIPRLEGI
STEIKVTEVGGLRDYDVALIGSSGQPGCILLYGGCKDTNTLDVPNHVTVI
RFNVLYHGLEALKETLVGALPKITKIRVTAEAECLQVFRASQAGKSGNAG
GMRVTKGTIIAAHLTFRVCRKAPGHRVVVYEGQIKELRRFKELVPSVELG
LECGVIMQDEFQFRTGDILQQYETYEEPRDVAEEYQKAELREKIMRDTAA
AEAL
Ligand information
>7pua Chain CA (length=501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaaauaaauuaaauuagu
cagaaauggaugccagccguugcgguaauuucuaugcuuuuaaauauuau
acaaaauuguuaagugcugauuuaaccaauaaaaauauaaauaauuuuac
cauuagguauuuuauucauauaauuaauaggauaauauuuguaguuuuug
auaccaugauaaggauuauaaauugaaaguguuaauaucauaaucaaaau
uuauuauuuauauuaaauauguauguguagauaaaauaagacccaccaau
uuuuauaauaaaaauaacgugcaguaauuaauauauuuauaaaaauauau
u
..............................<<<<<....<........<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
.......................................>.......<<<
.....<<<<<.....<<....>>.......>>>>>>>>.....>.>>>>.
.....<<<<<<<<<<....>>>>>>.>>>>..................<<
<....>>>..<<<<<...................................
......<.<<<<...................>>.>>>.............
..............................>>>>>........<<<..<<
<<<<.....>>>>>>...>>>........<<<<<<<<<....>>>>>>>>
>
Receptor-Ligand Complex Structure
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PDB7pua Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Q40 R45 Q47 P48 R60 T110 R111 S112 K126 R130 K133 Q140 A142 P144 K145 Y494 K497 P498 N500
Binding residue
(residue number reindexed from 1)		Q1 R6 Q8 P9 R21 T71 R72 S73 K87 R91 K94 Q101 A103 P105 K106 Y455 K458 P459 N461
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pua, PDBe:7pua, PDBj:7pua
PDBsum7pua
PubMed35042777
UniProtC9ZSN7

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