Structure of PDB 8x5d Chain I Binding Site BS01

Receptor Information
>8x5d Chain I (length=235) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPG
TSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVF
RDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFA
FSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGT
RGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
Ligand information
>8x5d Chain O (length=47) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaacuuaaaaccguguugcacugcaacccggaauucuugcacgucg
...............................................
Receptor-Ligand Complex Structure
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PDB8x5d Mycobacterium tuberculosis type III-A CRISPR/Cas system crRNA and its maturation have atypical features.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		G23 T52 S53 K55 R59 M95 T96 E126 N127 I129 L138 R139 Y195 G197 G198 S199 R202
Binding residue
(residue number reindexed from 1)		G22 T51 S52 K54 R58 M94 T95 E125 N126 I128 L137 R138 Y194 G196 G197 S198 R201
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8x5d, PDBe:8x5d, PDBj:8x5d
PDBsum8x5d
PubMed38218299
UniProtP9WJF9|CSM3_MYCTU CRISPR system Cms endoribonuclease Csm3 (Gene Name=csm3)

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