Structure of PDB 8u5h Chain I Binding Site BS01
Receptor Information
>8u5h Chain I (length=98) Species:
8355
(Xenopus laevis) [
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PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQRS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Ligand information
>8u5h Chain C (length=157) [
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acgtaaacatcctggagaatcccggtgccgaggccgctcaattggtcgta
gacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtttt
aaccgccaaggggattactccctagtctccaggcacgtgtcagatatata
catcctg
Receptor-Ligand Complex Structure
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PDB
8u5h
Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
Resolution
3.23 Å
Binding residue
(original residue number in PDB)
H39 R40 Y41 P43 G44 V46 R49 K64 L65 R69
Binding residue
(residue number reindexed from 1)
H2 R3 Y4 P6 G7 V9 R12 K27 L28 R32
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
Cellular Component
GO:0000786
nucleosome
GO:0005634
nucleus
GO:0005694
chromosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:8u5h
,
PDBe:8u5h
,
PDBj:8u5h
PDBsum
8u5h
PubMed
UniProt
P02302
|H3C_XENLA Histone H3.3C (Gene Name=h3-5)
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