Structure of PDB 8ti7 Chain I Binding Site BS01

Receptor Information
>8ti7 Chain I (length=131) Species: 6956 (Dermatophagoides pteronyssinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGSWQSYVDNQICQHVDCTLAAIANIQDGSIWAKFEKDDKKISPKELKTI
ADTIRQNPNGFLETGIHIGGEKYICIQADNQLVRGRRGSSALCIVATNTC
LLAAATVDGYPAGQLNNVIEKLGDYLRSNNY
Ligand information
Receptor-Ligand Complex Structure
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PDB8ti7 Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity.
Resolution2.397 Å
Binding residue
(original residue number in PDB)		S0 G1 S2 W3 Y6 Q10 W31 Y124 L125 Y130
Binding residue
(residue number reindexed from 1)		S1 G2 S3 W4 Y7 Q11 W32 Y125 L126 Y131
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0003785 actin monomer binding
Biological Process
GO:0042989 sequestering of actin monomers
GO:0044087 regulation of cellular component biogenesis
GO:0051128 regulation of cellular component organization
Cellular Component
GO:0005856 cytoskeleton
GO:0005938 cell cortex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8ti7, PDBe:8ti7, PDBj:8ti7
PDBsum8ti7
PubMed38662449
UniProtA0A2L0EBJ5

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