Structure of PDB 8sr5 Chain I Binding Site BS01

Receptor Information
>8sr5 Chain I (length=382) Species: 243233 (Methylococcus capsulatus str. Bath) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGEKSQAAFMRMRTIHWYDLSWSKEKVKINETVEIKGKFHVFEGWPETVD
EPDVAFLNVGMPGPVFIRKESYIGGQLVPRSVRLEIGKTYDFRVVLKARR
PGDWHVHTMMNVQGGGPIIGPGKWITVEGSMSEFRNPVTTLTGQTVDLEN
YNEGNTYFWHAFWFAIGVAWIGYWSRRPIFIPRLLMVDAGRADELVSATD
RKVAMGFLAATILIVVMAMSSANSKYPITIPLQAGTMRGMKPLELPAPTV
SVKVEDATYRVPGRAMRMKLTITNHGNSPIRLGEFYTASVRFLDSDVYKD
TTGYPEDLLAEDGLSVSDNSPLAPGETRTVDVTASDAAWEVYRLSDIIYD
PDSRFAGLLFFFDATGNRQVVQIDAPLIPSFM
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8sr5 Chain I Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8sr5 Product analogue binding identifies the copper active site of particulate methane monooxygenase
Resolution3.22 Å
Binding residue
(original residue number in PDB)		H33 H137 H139
Binding residue
(residue number reindexed from 1)		H1 H105 H107
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.18.3: methane monooxygenase (particulate).
External links
PDB RCSB:8sr5, PDBe:8sr5, PDBj:8sr5
PDBsum8sr5
PubMed38187819
UniProtG1UBD1|PMOB_METCA Particulate methane monooxygenase alpha subunit (Gene Name=pmoB1)

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