Structure of PDB 8sqw Chain I Binding Site BS01

Receptor Information

>8sqw Chain I (length=382) Species: 243233 (Methylococcus capsulatus str. Bath) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HGEKSQAAFMRMRTIHWYDLSWSKEKVKINETVEIKGKFHVFEGWPETVD
EPDVAFLNVGMPGPVFIRKESYIGGQLVPRSVRLEIGKTYDFRVVLKARR
PGDWHVHTMMNVQGGGPIIGPGKWITVEGSMSEFRNPVTTLTGQTVDLEN
YNEGNTYFWHAFWFAIGVAWIGYWSRRPIFIPRLLMVDAGRADELVSATD
RKVAMGFLAATILIVVMAMSSANSKYPITIPLQAGTMRGMKPLELPAPTV
SVKVEDATYRVPGRAMRMKLTITNHGNSPIRLGEFYTASVRFLDSDVYKD
TTGYPEDLLAEDGLSVSDNSPLAPGETRTVDVTASDAAWEVYRLSDIIYD
PDSRFAGLLFFFDATGNRQVVQIDAPLIPSFM

Ligand information

Ligand ID

InChI

InChI=1S/Cu/q+2

InChIKey

JPVYNHNXODAKFH-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Cu+2]
CACTVS 3.341	[Cu++]

Formula

Name

COPPER (II) ION

PDB chain

8sqw Chain I Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8sqw Product analogue binding identifies the copper active site of particulate methane monooyxgenase
Resolution	2.16 Å
Binding residue (original residue number in PDB)	H33 H137 H139
Binding residue (residue number reindexed from 1)	H1 H105 H107
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.14.18.3: methane monooxygenase (particulate).

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0046872	metal ion binding

	Cellular Component
GO:0016020	membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:8sqw, PDBe:8sqw, PDBj:8sqw
PDBsum	8sqw
PubMed	38187819
UniProt	G1UBD1\|PMOB_METCA Particulate methane monooxygenase alpha subunit (Gene Name=pmoB1)

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