Structure of PDB 8rw1 Chain I Binding Site BS01

Receptor Information
>8rw1 Chain I (length=188) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GISRDSRHKRAATGAKRAQFRKKRKFELGRQAANTKIGTKRIHPVRTRGG
NQKFRALRIETGNFSWASEGVARKTRITGVVYHPSNNELVRTNTLTKAAI
VQIDATPFRQWYESHYGQSLGKTSKNTERKWAARAAEAKIEHAVDSQFGA
GRLYAAISSRPGQSGRCDGYILEGEELAFYLRRLTAKK
Ligand information
>8rw1 Chain 2 (length=1798) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccgguccgacuuuaugucgcgcacugguuuucaaccggaucuuuccuuc
uggcuaaccuguacuccuugugggugcaggcgaaccaggacuuuuacuuu
gaaaaaauuagaguguucaaagcaggcgaaagcucgaauauauuagcaug
gaauaauggaauaggacguuugguucuauuuuguugguuucuaggaccau
cguaaugauuaauagggacggucgggggcaucaguauucaauugucagag
gugaaauucuuggauuuauugaagacuaacuacugcgaaagcauuugcca
aggacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugauca
gauaccgucguagucuuaaccauaaacuaugccgacuagggaucgggugg
uguuuuucuuaugacccacucggcaccuuacgagaaaucaaagucuuugg
guucuggggggaguauggucgcaaggcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuugacucaacacgggg
aaacucaccagguccagacacaauaaggauugacagauugagagcucuuu
cuugauuuugugggugguggugcauggccguucuuaguugguggagugau
uugucugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauaggg
uugcuggcacuugccgguugacucuucuuagagggacuaucgguuucaag
ccgauggaaguuugaggcaauaacaggucugugaugcccuuagacguucu
gggccgcacgcgcgcuacacugacggagccagcgaguacaaccuuggccg
agaggucuggguaaucuugugaaacuccgucgugcuggggauagagcauu
guaauuauugcucuucaacgaggaauuccuaguaagcgcaagucaucagc
uugcguugauuacgucccugcccuuuguacacaccgcccgucgcuaguac
cgauugaauggcuuagugaggccucaggauuugcuuagagaagggggcaa
cuccaucucagagcgaagaaucuggucaaacuuggucauuuagaggaacu
aaaagucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[................<<.....<<.
<<<.....>>>.>>......>>........<<<<<..<<....>>..>>>
>>[...((((((......<<<<<<<<<<<....>>>....<<......>>
)))))).....]...<<<<..<<<.....>>>.>>>>....]]]...}}}
}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<........
..>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<.
....>>>..>>>...............<<<<<<<<<.<.......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..))))))]
]]].........[[[{{.......{{...[[[.{{....<<<<<<<<<<<
.<<<<..<<<.......>>>....>>>>....>>>>>>>>>>>....<<<
<<<....<....<<<.......>>>....>....>>>>>>...<<<<<.<
<.......<<...<.......>..<<<....>>>....>>......>>.>
>..>>>.........[[[..((((((((....>>>>>>>>.)))))))).
]]].....}}....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<
......>>>......>.>>>>>>..>>.......<<....>>...>>>>.
..>>>>>.>>>...]]]...}}......<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<
.<<<........>>>>>>>>>>>..>>>...<<..}}>>...>>.....>
>>.]]].<<<......<<<<....>>>>....>>>..]]]]..<<<<<.<
<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<........>>...
.......<<<<<.<....<<<<<........<<.<<<........>>>.>
>......>>>>>...<<.<<<..<<<<<<<<<....<<<.<<<<......
>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<<
<<<<<<<<....>>>>>>.>>>>>>..>>>>.>>....<<<<<<.....>
>>>>>.......>>>>>....>>>.>>>...>.>>>>>>>.....>.>>>
>>...>>.>>>>.>>>.....<<<<<<<......<<.....<<<.<<<<.
...>>>>.>>>....>>.......>>>>>>>......<....<<<<<<..
........>>>>>>....>.....>>>>>>....<<<<<<<<.......>
>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<
<....<<<<<<<<.<<<..<<<<..<...<<<<<<..<............
.......>...>>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>
>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB8rw1 Structural basis of AUC codon discrimination during translation initiation in yeast.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		G2 R5 H9 K10 R11 T14 A16 F21 R22 K23 K24 R25 K26 F27 L29 G30 R31 Q32 A33 A34 K41 R42 I43 H44 R47 T48 R49 G50 N52 K54 R56 L58 R59 N64 S66 V72 A73 R74 K75 S86 T97 K98 S137 N139 T140 R142 S171 S172 R173 G175 Q176 S177 R179 D181
Binding residue
(residue number reindexed from 1)		G1 R4 H8 K9 R10 T13 A15 F20 R21 K22 K23 R24 K25 F26 L28 G29 R30 Q31 A32 A33 K40 R41 I42 H43 R46 T47 R48 G49 N51 K53 R55 L57 R58 N63 S65 V71 A72 R73 K74 S85 T96 K97 S124 N126 T127 R129 S158 S159 R160 G162 Q163 S164 R166 D168
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