Structure of PDB 8q5i Chain I Binding Site BS01

Receptor Information
>8q5i Chain I (length=182) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSKILSENPTELELKVAQAFVDLESQADLKAELRPLQFKSIKEIDVNGGK
KALAVFVPPPSLQAYRKVQTRLTRELEKKFPDRHVVFLAERRILPKPARK
ARKQQKRPRSRTLTAVHDKILEDLVFPTEIIGKRVRYLVGGNKIQKVLLD
SKDSTAVDYKLDSFQQLYSKLTGKQVVFEIPG
Ligand information
>8q5i Chain A (length=1558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagagaugauucauaauaacuuuucgaaucgcauggccuugugcugg
cgaugguucauucaaauuucugcccuaucaacuuucgaugguaggauagu
ggccuaccaugguuucaacggguaacggggaauaaggguucgauuccgga
gagggagccugagaaacggcuaccacauccaaggaaggcagcaggcgcgc
aaauuacccaaucccgacacggggagguagugacaauaaauaacgauaca
gguuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauug
gagggcaagucuggugccagcagccgcgguaauuccagcuccaaaagcgu
auauuaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuugg
cugcagccgagccuuuuuuacuuugaaaaaauuagaguguucaaagcagg
ccuuugcucgaauauauuagcauggaauaauagaauaggacguuauaucg
uaaugauuaauagggacggucggggguaucaguauucaguugucagaggu
gaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuaccaag
gacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugaucaga
uaccgucguagucuuaaccauaaacuaugccgacuagggaucgguuguug
uucugacgcaaucggcaccuuacgagaaaucaaagucuuuggguucuggg
gggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggcacc
accaggaguggagccugcggcuuaauuugacucaacacggggaaacucac
cagguccagacacugagagcugugggugguggugcauggccguucuuagu
ugguggagugauuugucugcuuaauugcgauaacgaacgagaccuuaacc
uacuaaauagugccacuucuuagagggacuaucgauuucaagucgaugga
aguuugaggcaauaacaggucugugaugcccuuagacguucugggccgca
cgcgcgcuacacugacggagccagcgaguauaagccuuggccgagagguc
ugggaaaucuugugaaacuccgucgugcuggggauagagcauuguaauug
uugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguu
gauuacgucccugcccuuuguacacaccgcccgucgcuacuaccgauuga
auggcuuagugaggccuccggauuggcgagaagcuggucaaacuugguca
uuuagaggaaguaaaagucguaacaagguuuccguaggugaaccugcgga
aggaucau
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
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......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<...........>>>>>>.....>...<<<<..<<<.....>>>.>
>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<.....
..>>>>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.>
>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>....
.....<<<....<<<<...>>>>..>>>..>....>.>.....<<<<...
<..>...>>>>......<<..<...........>..>>.........<<<
<<((....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>>>
>>>>>>.........<<<((.....<.<<...<<<.<<....<<<<<<<<
<<..>>>>>>>>>>...<<<<<.<<.......<<...<.......>..<<
<....>>>....>>......>>.>>..>>>.........<<<..<..>>>
>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<..
....>>>......>.>>>>>>..>>.......<<....>>...>>>>...
>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<....
.>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<..
<<..>>.>>>>>>>>..>>>...<<..))>>...>>.....>>>.>>>.<
<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..
<<.<<<<<<..<<<.<<<<.<......<<........>>..........<
<<<<.<....<<<........>>>...<<.<<<..<<.<<<<<<....<<
<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<
..<<<<..<<<<.>>>>..>>>>.>>....<<<<<<.....>>>>>>...
....>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>..
>>>>.>>>.....<<<<<<<......<<......<<<.<<<<....>>>>
.>>>....>>.......>>>>>>>...........<<<<<<.........
.>>>>>>..........>>>>>>....<<<<<<<<.......>>>>>>>>
......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<
<<<<<<.<<<..<<<<..<...<<<.>>>...>..>>>>..>>>.>>>>>
>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>
>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q5i Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Resolution2.45 Å
Binding residue
(original residue number in PDB)		P60 P61 R92 R93 I94 R100 R103 K104 Q106 K107 R108 P109 R110 S111 R112 T113 L114 T115 G174
Binding residue
(residue number reindexed from 1)		P59 P60 R91 R92 I93 R99 R102 K103 Q105 K106 R107 P108 R109 S110 R111 T112 L113 T114 G173
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8q5i, PDBe:8q5i, PDBj:8q5i
PDBsum8q5i
PubMed
UniProtA0A8H6C655

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