Structure of PDB 8p2i Chain I Binding Site BS01

Receptor Information
>8p2i Chain I (length=58) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKACRHCHYITSEDRCPVCGSRDLSEEWFDLVIIVDVENSEIAKKIGAKV
PGKYAIRV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8p2i Chain I Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8p2i Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment
Resolution3.4 Å
Binding residue
(original residue number in PDB)
C6 C9 C18 C21
Binding residue
(residue number reindexed from 1)
C4 C7 C16 C19
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:8p2i, PDBe:8p2i, PDBj:8p2i
PDBsum8p2i
PubMed38709902
UniProtQ8U440|SPT4_PYRFU Transcription elongation factor Spt4 (Gene Name=spt4)

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