Structure of PDB 8ovw Chain I Binding Site BS01

Receptor Information
>8ovw Chain I (length=679) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLILDDIILSLTKTTLSLLYEKSKQYGLSSPQLQALVRLLCETSIIDTVT
KVYIVENCFLPDGYLTKELLLEIINHLGTPTVFSRYRIQTPPVLQSALCK
WLVHVNISSSIWLHLWQFSFLQKWITPLVIWQATTPVDVKPWKLSIIKRC
AMHPGYRDAPGSATLILQRFQCLVGASSQITESIITINCNRKTLKSHRNL
KLDAHFLSILKRILSRAHPANFPADTVQNTIDMYLSEIHQLGADSTVSLW
DVTSLEQLAQNWPQLHIPNDVDYMMKPRKVMSRDSLKHLYSSIILIKNSR
DESSSPYEWCIWQLKRCFAHQIETPQEVIPIIISVSSMDNKLSSRIIQTF
CNLKYLKLDELTLKKVCGGILPLWKPELISGTREFFVKFMASIFMWSTRD
GHDNNCTFSETCFYVLQMITNWVLDDKLIALGLTLLHDMQSLLTLDKIFN
NATSNRFSTMAFISSLDILTQLSKQTKSDYAIQYLIVGPDIMNKVFSSDD
PLLLSAACRYLVATKNKLMQYPSTNKFVRMQNQYIMDLTNYLYRNKVLSS
KSLFGVSPDFFKQILENLYIPTADFKNAKFFTITGIPALSYICIIILRRL
ETAENTKIKFTSGIINEETFNNFFRVHHDEIGQHGWIKGVNNIHDLRVKI
LMHLSNTANPYRDIAAFLFTYLKSLSKYS
Ligand information
Receptor-Ligand Complex Structure
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PDB8ovw Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
C213 N214 R215
Binding residue
(residue number reindexed from 1)
C189 N190 R191
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006270 DNA replication initiation
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0034087 establishment of mitotic sister chromatid cohesion
GO:0051301 cell division
GO:0051321 meiotic cell cycle
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ovw, PDBe:8ovw, PDBj:8ovw
PDBsum8ovw
PubMed37506202
UniProtQ12748|CENPI_YEAST Inner kinetochore subunit CTF3 (Gene Name=CTF3)

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