Structure of PDB 8om3 Chain I Binding Site BS01

Receptor Information
>8om3 Chain I (length=231) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPRRIVPKLATFYSANPNHEDRINRLERLLRKYIKLPSQNNNEAQQTKAP
WISFDEYALIGGGTKLKPTQYTQLLYMLNKLHNIDPQLTNDEITSELSQY
YKKSSMLSNNIKIKTLDEFGRSIAVGKRKSSTAKVFVVRGTGEILVNGRQ
LNDYFLKMKDRESIMYPLQVIESVGKYNIFATTSGGGPTGQAESIMHAIA
KALVVFNPLLKSRLHKAGVLTRDYRHVERKK
Ligand information
>8om3 Chain r (length=1487) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacac
augcgaaucauacguuuauuauugauaagauaauaaauaugugguguaaa
cgugaguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacu
uaauauauaaaaaggauauauaauauauuuaucuauagucaagccaauaa
ugguuuagguaguagguuuauuaagaguuaaaccuagccaacgauccaua
aucgauaaugaaaguuagaacgaucacguugacucugaaauauagucaau
aucuauaagauacagcagugaggaauauuggacaaugaucgaaagauuga
uccaguuacuuauuaggaugauauauaaauauauauauauaaauugauua
aaaauaaaauccauaaauaauuaaaauaaugauauuaauuaccauauauu
uuuauauggauauauuuuaauaguccugacuaauauuugugccagcaguc
gcgguaacacaaagagggcgagcguuaaucauaaugguuuaaaggauccg
uagaaugaauuauauauuauaauuuagaguuaauaaaauuaauuaaagaa
uuauaauaguaaagaugaaauaaauaauuauaagacuaauauaugugaaa
auauuaauuaaauauuaacugacauugagggauuaaaacuagaguagcga
aacggauucgauacccguguaguucuaguaguaaacuaugaauacaauua
uuuauauauauauauauaaauaauaaaugaaaaugaaaguauuccaccug
aagaguacguuagcaauaaugaaacucaaaacaauagacgguuacagacu
uaagcaguggagcauguuauuuaauucgauaauccacgacuaaccuuacc
auauuuugaauauuauaauaauuaaauuauuauauuacaggcguuacauu
guugucuuuaguucgugcugcaaaguuuuagauuaaguucauaaacgaac
aaaacuccauauauauaauuuuaauuauauauaauuuuauauuauuuauu
aauauaaagaaaggaauuaagacaaaucauaaugauccuuauaauauggg
uaauagacgugcuauaauaaaaugauaauaaaauuauauaaaauauauuu
aauuauauuuaauuaauaauauaaaacauuuuaauuuuuaauauauuuuu
uuauuauauauuaauaugaauuauaaucugaaauucgauuauaugaaaaa
agaauugcuaguaauacguaaauuaguauguuacggugaauauucuaacu
guuucgcacuaaucacucaucacgcguugaaacauauuauuaucuuauua
uuuauauaauauuuuuuaauaaauuuauuaauuuauauuuauuuauauca
gaaauaauaugaauuaaugcgaaguugaaauacaguuaccguaggggaac
cugcggugggcuuauaaauaucuuaaauauucuuaca
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<......<<<
.<<<..<<<..<<<<<<<<<<<<.....>>>>>>>>>>..>>>>>.....
<<<........<<<<<.<<.........<<<<<<<<.<<<<.......>>
>>...........<<<<<<<<.>>>>>>>>.>>>>>>>>....>>>>>>>
<<<....<<<..<<<<<<<<........>>>>>>>>>>>......>>>..
<<<<.<<<<....>>>>...>>>>.>>><<<<<<.........>>>>>><
<<<.....>>>>..>>>>>>.........<<<....<<<<....>>>>..
>>>...>.>>>>>>.<<<<..<<<<<<........>>>>>>..<<.....
.>>.....>>>>..<<<<<<<<..............>>>>><<<<<<<..
..>>>>>>><<..>>>>>....<<<<<(((.....<<<<.....<<.)))
>>.......>>>>.>>>>>..>>>>>>>>>.....<<<((.....<<<<.
..<.<<.<<<<<<<...>>>>>>>...<<<<<<<<...<<<<<<<<<<..
<<<<<<<...................>>>>>>>..>>.......<<....
>>.>>>>>>>>.>>>>>>>>...>>>...>>>>....<<<<<<...<<..
.<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.<<<<
<<<<<<<<<..>>>>>>>>>>>>>..<<..))>>....>>>>>>.>>>.<
<.......<<<<....>>>>.....>>..)))).]<<.<<...<<<<...
..<<<<<<..<<<<<<<<<<......<<........>>..........<<
<<<<<.....<<.<<<<<<<<<<.>>>>>>>>>>.>>.<<<.<<<..<<<
<<<<<<<<..<<<<<<<<<....>>>....<<......>>....>>>>>>
.....<<<.<<<<<<<<........>>>>>>>>..<<<<<<<<<.....>
>>>>>>>>....>>>...>>>>>.>>>...>>>>>>>>>...>>>>>>>.
..>>.>>>>>>>>.....<<<<<<........<<<..<<..<<<<<<...
...>>>>>>..>>....>>>......>>>>>>......<<<<<.......
.>>>>>..........<....<<<<<<<........>>>>>>>....>..
...>>>>>>....<<.<<<<<.........>>>>>>>...........>>
>>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<<<<<.<<<...<<
<..<<<.<<<<<...<<<<<<<..>>>>>>>...>>>>>>>>..>>>..>
>>>>>>>>>>>..>>>>>>>>..>.>>>..>.....<<<<<<<<<....>
>>>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8om3 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Resolution2.87 Å
Binding residue
(original residue number in PDB)
R63 I66 K67 Q77 K97 K99 P100 T101 T104 Q105 Y108 N142 K159 R160 K161 S162 K166 R181 Y186 L188 K191 T214 S216 G217 G218 G219 T221 Q223 K243 S244 H247 L252 T253 R254 Y256 R257 H258 V259 E260 R261 K263
Binding residue
(residue number reindexed from 1)
R31 I34 K35 Q45 K65 K67 P68 T69 T72 Q73 Y76 N110 K127 R128 K129 S130 K134 R149 Y154 L156 K159 T182 S184 G185 G186 G187 T189 Q191 K211 S212 H215 L220 T221 R222 Y224 R225 H226 V227 E228 R229 K231
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8om3, PDBe:8om3, PDBj:8om3
PDBsum8om3
PubMed38199006
UniProtP38120|RT09_YEAST Small ribosomal subunit protein uS9m (Gene Name=MRPS9)

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