Structure of PDB 8jke Chain I Binding Site BS01

Receptor Information
>8jke Chain I (length=254) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEEEESGALRFGVLGPVRAWRDGETLATGSPQQRALLAALLLREGRTATA
GELIDALWGEEPPSQALAAVRTYASRLRKVLDPGVLVSESGGYAVRGLAE
GALDLARAQDLASAAEKARSAGDLCHARDLLRRALDLWDGEVLAGVPGPY
AQTQRVRLGEWRLQLLETRLDMDLDQGCHAEAVSELTALTAAHPLRERLR
ELLMLALYRSGRQAEALAVYADTRRLLADELGVDPRPGLQELQQRILQAD
PALA
Ligand information
>8jke Chain O (length=61) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccggagcgttcagcgttcgtttatctccccctggcactgtcatctccgtc
agaccgtcgca
Receptor-Ligand Complex Structure
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PDB8jke Structural and functional characterization of AfsR, a SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces
Resolution3.67 Å
Binding residue
(original residue number in PDB)		S46 P47 Q48 Q81 A85 Y89
Binding residue
(residue number reindexed from 1)		S30 P31 Q32 Q65 A69 Y73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0031409 pigment binding
GO:0043531 ADP binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8jke, PDBe:8jke, PDBj:8jke
PDBsum8jke
PubMed38427710
UniProtP25941|AFSR_STRCO Regulatory protein AfsR (Gene Name=afsR)

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