Structure of PDB 8jib Chain I Binding Site BS01

Receptor Information
>8jib Chain I (length=660) Species: 7159 (Aedes aegypti) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNYKKNLLLLYDRPREPIFMGKGKSVFDVPDNYLTDRYRPIGPEIQNRFG
ELAEERIPVRSIALPDLRIPMSLGRQEQFSLFIPRHRKIAARLIDIFMGM
RNIEELQSCAVFARDRINPYLFNYALSVALLHRRDTKNLDLPSVVEVFPD
KYVDSRVFEQIREEATVVPEGMRMPIVIPKDFTASDLDEEHRLWYFREDI
GVNLHHWHWHLVYPFEASNRAIVDKDRRGELFYYMHSQLIARYNFERFCN
RLQRVKRLNNLREPIAEGYFPKLDSLVASRTWPGRVDNAVIKDLNRELDQ
IKQDVSDLERWIDRIYEAVHQGYVVDESGNRIFLDEEKGIDILGNIIESS
ILSPNRQLYGDMHNVGHVFLSYTHDPDHRHLESFGVMGDVATAMRDPVFY
RWHSFIDDIFQEHKIKLPAYTKSQLTYEGISVTGIIVQSEGAPVNTLHTY
WQQSDVDLSRGMDFVPRGNVFARFTHLQHAPFQYVIQIDNTSDAQRMGFV
RIFMAPKNDERGQPMLFRDQRLFMVEMDKFLVALRPGANRIRRRSNESTV
TIPFERTFRFCGCGWPAHMLVPKGLPEGFPADLFVMVSNYEDDRVVQDLV
GTCNDYCGVRDRLYPDRKAMGFPFDRLARTGVDRLSNFVTPNMAIQSVNV
IHIDKTVPRT
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8jib Chain I Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8jib Mosquitoes have evolved two types of prophenoloxidases
Resolution3.15 Å
Binding residue
(original residue number in PDB)		H206 H210 H236
Binding residue
(residue number reindexed from 1)		H206 H210 H236
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004503 tyrosinase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006582 melanin metabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jib, PDBe:8jib, PDBj:8jib
PDBsum8jib
PubMed
UniProtQ16G28

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