Structure of PDB 8d3p Chain I Binding Site BS01

Receptor Information
>8d3p Chain I (length=218) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASNEEDRYLMLSGLQHFQFCKRQWALIHIEQQWEENVRTIEGQHLHKKAD
QPFMKEKRGSKLTVRAMPIQSKNLQISGICDVVEFVQDSEGIELSGVSGS
YKAFPVEYKRGKPKKGDEDIVQLVAQAMCLEEMLVCRIDKGYLFYNEIKH
RVEVPITDALRDKVVQMAKEMHHYYENRHTPKVKTGPFCNNCSLQSICLP
KLMNKRSVKRYIEGRLSE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d3p PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Resolution4.26 Å
Binding residue
(original residue number in PDB)		M11 L12 S13 H17 F20 Q24 I28 W34 R39 T40 G79 I80 E108 K110 R111 K115 P188
Binding residue
(residue number reindexed from 1)		M10 L11 S12 H16 F19 Q23 I27 W33 R38 T39 G78 I79 E107 K109 R110 K114 P187
Enzymatic activity
Enzyme Commision number 3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Gene Ontology
Molecular Function
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8d3p, PDBe:8d3p, PDBj:8d3p
PDBsum8d3p
PubMed36272411
UniProtA0A4Y7WTW2

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