Structure of PDB 8a3y Chain I Binding Site BS01

Receptor Information
>8a3y Chain I (length=116) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKIT
HEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMR
LYYVCTAPHCGHRWTE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8a3y Chain I Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8a3y Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		C17 C39 C42
Binding residue
(residue number reindexed from 1)		C8 C30 C33
Annotation score1
Gene Ontology
Molecular Function
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0001193 maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005730 nucleolus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8a3y, PDBe:8a3y, PDBj:8a3y
PDBsum8a3y
PubMed35858621
UniProtP60899|RPB9_PIG DNA-directed RNA polymerase II subunit RPB9 (Gene Name=POLR2I)

[Back to BioLiP]