Structure of PDB 7zmk Chain I Binding Site BS01

Receptor Information
>7zmk Chain I (length=219) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEGGKWTVFQKRF
NGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFE
NNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFS
TFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLSYANGINWA
QWKGFYYSLKRTEMKIRRA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7zmk Chain I Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zmk MFAP4-targeted immunotherapy inhibits retinal neovascularization and vascular leakage
Resolution3.4 Å
Binding residue
(original residue number in PDB)		D170 D172 F174 V175 Q176
Binding residue
(residue number reindexed from 1)		D155 D157 F159 V160 Q161
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7zmk, PDBe:7zmk, PDBj:7zmk
PDBsum7zmk
PubMed
UniProtP55083|MFAP4_HUMAN Microfibril-associated glycoprotein 4 (Gene Name=MFAP4)

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