Structure of PDB 7xoi Chain I Binding Site BS01

Receptor Information
>7xoi Chain I (length=465) Species: 927772 (Aspergillus sojae NBRC 4239) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGDDLYVKDLSGCPGYKATKHWQTRSGFYADLTLAGPACNVFGTDLPDLK
LEVEYQTSDRLHVKILDTNNTVYQVPDSVFPRPGFGEWCSPKDSKLKFDF
QADPFSFTVSRTDTGEVLFDTTGNKLVFESQYVYLKTHLPQNPHLYGLGE
HSDAFMLNTTNYTRTIYTRDAYGTPQGENLYGAHPIYFDHRQTGTHGVFL
LNSNGMDIFIDNNATQYLEYNIIGGVLDFYFIAGPSPRDVAIQYAEITQT
PLMTPYWGLGYHQCKYGYQDVYEVAAVVANYSTNNIPLETIWTDIDYMDR
RRIFTIDPERFPANLYKDLVDTIHARDQHYIVMVDPAVYYKESNPALDEG
LRYDIFMKENNGSEYQGVVWAGPSHFPDWFHPDSQQYWSEQFLAFFDGTN
GPDIDALWIDMNEPANFYNRPYPGNNTTPENFAEVDGDPPAAPAVRDGPD
APIPGFPASLQPNWV
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain7xoi Chain g Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xoi Structural basis for proteolytic processing of Aspergillus sojae alpha-glucosidase L with strong transglucosylation activity.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y296 D324 D440 M441
Binding residue
(residue number reindexed from 1)		Y266 D294 D410 M411
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.20: alpha-glucosidase.
3.2.1.21: beta-glucosidase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007618 mating
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xoi, PDBe:7xoi, PDBj:7xoi
PDBsum7xoi
PubMed35688347
UniProtA0A5N6DPG0

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