Structure of PDB 7qoo Chain I Binding Site BS01

Receptor Information
>7qoo Chain I (length=618) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQAEEDALQMAVGYFEKGPIKASQNKDKTLEKHLKTVENVAWKNGLASEE
IDILLNIALSGKFGNAVNTRILKCMIPATVISEDSVVKAVSWLCVGKCSG
STKVLFYRWLVAMFDFIDRKEQINLLYGFFFASLQDDALCPYVCHLLYLL
TKKENVKPFRVRKLLDLQAKMGMQPHLQALLSLYKFFAPALISVSLPVRK
KIYFKNSENLWKTALLAVKQRNRGNRSGSFPLEQLQSFPQLLQNIHCLEL
PSQMGSVLNNSLLLHYINCVRDEPVLLRFYYWLSQTLQEECIWYKVNNYE
HGKEFTNFLDTIIRAECFLQEGFYSCEAFLYKSLPLWDGLCCRSQFLQLV
SWIPFSSFSEVKPLLFDHLAQLFFTSTIYFKCSVLQSLKELLQNWLLWLS
MDIHMKPVTNSPLETTLGGSMNSVSKLIHYVGWLSTTAMRLESNNTFLLH
FILDFYEKVCDIYINYNLPLVVLFPPGIFYSALLSLDTSILNQLCFIMHR
YRKNLTAAKKNELVQKTKSEFNFSSKTYQEFNHYLTSMVGCLWTSKPFGK
GIYAEYKNSLNVVHHPSFLSYAVSFLLQESPEERTVNVSSIRGKKWSWYL
DYLFSQGLQGLKLFIRSS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7qoo Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		R452 S453 Q457 Y488
Binding residue
(residue number reindexed from 1)		R343 S344 Q348 Y379
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0007059 chromosome segregation
GO:0007548 sex differentiation
GO:0034080 CENP-A containing chromatin assembly
GO:0034508 centromere complex assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0016604 nuclear body

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qoo, PDBe:7qoo, PDBj:7qoo
PDBsum7qoo
PubMed35525244
UniProtQ92674|CENPI_HUMAN Centromere protein I (Gene Name=CENPI)

[Back to BioLiP]