Structure of PDB 7pli Chain I Binding Site BS01

Receptor Information
>7pli Chain I (length=451) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSG
KTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVM
DEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDP
LAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKK
DCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAA
RGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEAQR
ANIISDMLQIKLNWQTPSSIATLEAEMATLCIDGGKKAKMRPGDVLGALT
GDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRL
L
Ligand information
>7pli Chain L (length=22) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggacauauggcuguucgccauu
......<<<<<.....>>>>>.
Receptor-Ligand Complex Structure
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PDB7pli Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		P79 T80 R81 G108 T129 G131 R132 D135 F163 N249 T250 K251 G273 R280 T298 W320
Binding residue
(residue number reindexed from 1)		P77 T78 R79 G106 T127 G129 R130 D133 F161 N247 T248 K249 G271 R278 T296 W318
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0033677 DNA/RNA helicase activity
GO:0034458 3'-5' RNA helicase activity
GO:0043531 ADP binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pli, PDBe:7pli, PDBj:7pli
PDBsum7pli
PubMed37221012
UniProtP21693|DBPA_ECOLI ATP-dependent RNA helicase DbpA (Gene Name=dbpA)

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