Structure of PDB 7o9m Chain I Binding Site BS01

Receptor Information
>7o9m Chain I (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPSPPSPPQEEIGLIRLLRRE
IAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQVLKPFL
EDSKYQNLLPLFVGHNMLLVSEEPKVKEMVRILRTVPFLPLLGGCIDDTI
LSRQGFINYSKLPSLPLVQGELVGGLTCLTAQTHSLLQHQPLQLTTLLDQ
YIREQ
Ligand information
>7o9m Chain A (length=1454) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccaaaccuuagccaa
accauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcgcaa
uagauauaguaccgcaagggaaagaugaaaaaaccaagcauaauauagca
aggacuaaccccuauaccuucugcauaaugaauuaacuagaaauaacuuu
gcaaggagagccaaagcuaagacccccgaaaccagacgagcuaccuaaga
acagcuaaaagagcacacccgucuauguagcaaaauagugggaagauuua
uagguagaggcgacaaaccuaccgagccuggugauagcugguuguccaag
auagaaucuuaguucaacuuuaaauuugcccacagaacccucuaaauccc
cuuguaaauuuaacuguuaguccaaagaggaacagcucuuuggacacuag
gaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguaggccua
aaagcagccaccaauuaagaaagcguucaagcucaacacccacuaaaaaa
ucccaaacauauaacugaacuccucacacccaauuggaccaaucuaucac
ccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccucc
gcauaagccugcgucagauacacugaacugacaauuaacagcccaauauc
uacaaucaaccaacaagucauuauuacccucacugucaacccaacacagg
caugcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuu
accccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagag
gcaccgccugcccagugaucacuuguuccuuaaauagggaccuguaugaa
uggcuccacgaggguucagcugucucuuacuuuuaaccagugaaauugac
cugcccgugaagaggcgggcauaacacagcaagacgagaagacccuaugg
agcuuuaauuuauuaaugcaaacaccugcauuaaaaauuucgguuggggc
gaccucggagcagaacccaaccuccgagcaguacaugcuaagacuucacc
agucaaagcgaacacucaauugauccaauaacuugaccaacggaacaagu
uacccuagggauaacagcgcaauccuauucuagaguccauaucaacaaua
ggguuuacgaccucgauguuggaucaggacaucccgauggugcagccgcu
auuaaagguucguuuguucaacgauuaaaguccuacgugaucugaguuca
gaccggaguaauccaggucgguuucuaucuacuuucaaauuccucccugu
acgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccgu
aaaugauaucaucucaacuuaguauuauacccacacccacccaagaacag
gguu
<<<.......<<<<..................................<.
.....>...............<<.....>>.............>>.>>..
...........<<....>>.................>>>...........
<<<.......>>>...<.<<......>>.>.<<<<<<.........<<<.
<<..<<....>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<<
<..<<<.....>>>...<<<..<<<<........>>>>.>>>....>>>.
>>>>>...<<.......>>......>.>>>>......>.>>..<<<<<<.
...<<<<....>>>>.<<.<<<<<<<<<<.....<<..........>>..
...>>>>>>>>>>..>>..<<<<<<<<<<....(.>>>>>>>>>>...<<
<......>>>....<<<.<<<...<..............<....<<<...
......>>>....>.......<<<......>>>.................
...............>...>>>>>>........>>>>>>...<<<<<...
...>>>>>.........>>>>>>.......<<..<<<....>>><<<<..
<<<<........<<<<<..........>>>>>......<<<...<<<<..
.....................>>>>.......>>>.....<<......>>
.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........<......
<<<<<<..<<<.........>>>...<<<<<<.............>>>>>
>....<<<.....<<<<..>>>>.<<<<<<.....>>>>>>.........
.>>>....>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.........
..<<<<<........>>>>>.......<<..<<<.<<<....<<<<<.<<
<<<<..<<<<<.<<<<<<<<......>>>>>>>>>>>>>..<<<<.[.[.
>>>><<<<<.............>>>>>..<<.....<<<..<<<<.....
>>>>..>>>.....>>.........<<<....>>>............>>>
>..>>>>>>>..........<<<<<<<<<...<<.......>>...>>>>
>>>>>)....].].....<<<<<..<<<<<..<<.<<<<<<......>>>
>>>...>>.<<<<<.....>>>>>.....>>>>>......>>>>>.....
<<<<<<<....>>>.>>>>...>>>..>>>.>>.....<<<.<<<.....
............>>>.>>><<<<<...<<<....>>>.>>>>>......<
<<................>>>.................<<<<.......>
>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7o9m Structural basis for late maturation steps of the human mitoribosomal large subunit.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		R38 H41 Q43 K46 A106 R113 V125 P127 N128 G149 H150
Binding residue
(residue number reindexed from 1)		R3 H6 Q8 K11 A71 R78 V90 P92 N93 G114 H115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7o9m, PDBe:7o9m, PDBj:7o9m
PDBsum7o9m
PubMed34135318
UniProtQ7Z7H8|RM10_HUMAN Large ribosomal subunit protein uL10m (Gene Name=MRPL10)

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