Structure of PDB 7b0n Chain I Binding Site BS01

Receptor Information
>7b0n Chain I (length=191) Species: 4952 (Yarrowia lipolytica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INIYAGGSAAAAPPAGFRIHRPATWEESEEGALSKATKYFLLAEMFRGLY
VVLEQFFRAPYTIYYPFEKGPVSPRFRGEHALRRYPSGEERCIACKLCEA
ICPALAITIDAEERIDGSRRTTKYDIDMTKCIYCGYCQESCPVDAIVETP
NVEYATETREELLYNKEKLLANGDKWELELQYALDADAPYR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7b0n Chain I Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7b0n A conserved arginine residue is critical for stabilizing the N2 FeS cluster in mitochondrial complex I.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		C327 I328 A329 C330 K331 C333 C376
Binding residue
(residue number reindexed from 1)		C92 I93 A94 C95 K96 C98 C141
Annotation score4
Enzymatic activity
Enzyme Commision number 1.6.99.3: Deleted entry.
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:7b0n, PDBe:7b0n, PDBj:7b0n
PDBsum7b0n
PubMed33640456
UniProtQ9UUT8

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