Structure of PDB 7ap8 Chain I Binding Site BS01

Receptor Information

>7ap8 Chain I (length=464) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TDEMTYNLYDLFFNTLDMYLRQKKISILVNDDVVIVSYKPEIKKIPFNMK
NLLPYLEKNLDQLRFSKKYLDFAYLCRHIGIPISKKKYNVRYVFLYKIDG
LSIPIIIKDFLDVKYVYLENTGKIYKNSFSEDHNNSLSDWGKVIIPLLKD
RHLYSYIFLSSYHLHSYYTDLIARDEPVFVKRKKLDIIEIDEPEAWKRDV
RVEFAPCEHQIRLKEAMKVDANYFTKINNFANEFIYYEDGVAYCRVCGIN
QRSALEPNYDVESRGEELPLSALKFFDTSTIIVKTMAPVHTCVEQKIVAP
TPSVEPTDASLKNFKELTCDEDIKILIRVHDTNATKLVIFPSHLKIEIER
KKLIIPLKSLYITNTLKYYYSNSYLYVFRFGDPMPFEEELIDHEHVQYKI
NCYNILRYHLLPDSDVFVYFSNSLNREALEYAFYIFLSKYVNVKQWIDEN
ITRIKELYMINFNN

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

7ap8 Chain I Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7ap8 Structural basis of the complete poxvirus transcription initiation process.
Resolution	3.15 Å
Binding residue (original residue number in PDB)	C326 H328 C363 C366
Binding residue (residue number reindexed from 1)	C207 H209 C244 C247
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003700	DNA-binding transcription factor activity
GO:0016779	nucleotidyltransferase activity

	Biological Process
GO:0006353	DNA-templated transcription termination
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:7ap8, PDBe:7ap8, PDBj:7ap8
PDBsum	7ap8
PubMed	34556871
UniProt	Q1PIU7

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