Structure of PDB 7afh Chain I Binding Site BS01

Receptor Information
>7afh Chain I (length=127) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLE
LVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGF
VTRDARQVERKKVGLRKARRRPQFSKR
Ligand information
>7afh Chain 1 (length=456) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaacc
uuaccuggucuugacauccacggaaguuuucagagaugagaaugugccuu
cgggaaccgugagacaggugcugcauggcugucgucagcucguguuguga
aauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcca
gcgguccggccgggaacucaaaggagacugccagugauaaacuggaggaa
gguggggaugacgucaagucaucauggcccuuacgaccagggcuacacac
gugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgga
ccucauaaagugcgucguaguccggauuggagucugcaacucgacuccau
gaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacgu
ucccgg
<<<.<<.<<<<<...<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<<..
..>>..>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....
>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....<<.
.<<<.....>>>>>.....>>>>>>.....<<<<<.....>>>>>.....
...>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>
>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>...
.>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>.
...>......>>>>>....<<<<<<<.........>>>>>>>......>>
...>>>
Receptor-Ligand Complex Structure
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PDB7afh A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Resolution3.59 Å
Binding residue
(original residue number in PDB)
Q5 Y7 T9 R11 K13 S14 R18 F20 R33 Y64 G69 G70 G71 S73 R85 R95 R99 V104 T105 R106 A108 R109 Q110 V111 E112 R113 K114 K115 V116 G117 R119 K120 R122 R123 R124 Q126 F127 S128 K129 R130
Binding residue
(residue number reindexed from 1)
Q2 Y4 T6 R8 K10 S11 R15 F17 R30 Y61 G66 G67 G68 S70 R82 R92 R96 V101 T102 R103 A105 R106 Q107 V108 E109 R110 K111 K112 V113 G114 R116 K117 R119 R120 R121 Q123 F124 S125 K126 R127
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7afh, PDBe:7afh, PDBj:7afh
PDBsum7afh
PubMed34088665
UniProtP0A7X3|RS9_ECOLI Small ribosomal subunit protein uS9 (Gene Name=rpsI)

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