Structure of PDB 6rfl Chain I Binding Site BS01

Receptor Information
>6rfl Chain I (length=773) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSKETILIEIIPKIKAYLLDANISPKSYDDFISRNKNIFVINLYNVSTIT
EEDIRLLYTTIEQNIDADDQTLVAIFSYIGYKFEQAVKEEISTSLSFNDK
NTTDEMTYNLYDLFFNTLDMYLRQKKISILVNDDVVIVSYKPEIKKIPFN
MKNLLPYLEKNLDQLRFSKKYLDFAYLCRHIGIPISKKKYNVRYVFLYKI
DGLSIPIIIKDFLDVKYVYLENTGKIYKNSFSEDHNNSLSDWGKVIIPLL
KDRHLYSYIFLSSYHLHSYYTDLIARDEPVFVKRKKLDIIEIDEPEAWKR
DVRVEFAPCEHQIRLKEAMKVDANYFTKINNFANEFIYYEDGVAYCRVCG
INIPIFNLDAADVIKNTVIVSTFNKTIFLSEPYSYFVHSQRFIFNIIMSF
DNIMKSQTWVMKYNINRLILNFLIDINSRRQEYEKKFSSEIKRGLFFLRL
SANLFETELFYVSKMLNLNYIVALVIILNSSADFIVSYMTSKNKTVEEST
LKYAISVVIYDFLVKTRICEKGSLDTIVLFTDVYTSIMPEELDLHFQRIT
LELRKLVSIQRSALEPNYDVESRGEELPLSALKFFDTSTIIVKTMAPVHT
CVEQKIVAPTPSVEPTDASLKNFKELTCDEDIKILIRVHDTNATKLVIFP
SHLKIEIERKKLIIPLKSLYITNTLKYYYSNSYLYVFRFGDPMPFEEELI
DHEHVQYKINCYNILRYHLLPDSDVFVYFSNSLNREALEYAFYIFLSKYV
NVKQWIDENITRIKELYMINFNN
Ligand information
>6rfl Chain U (length=63) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaugguguaaugguuagcacucuggacuuugaauccagcgauccgaguu
caaaucucggugg
<<<..<<<<........>>>>.<<<<<.......>>>>>....<<<<<..
.....>>>>>>>>
Receptor-Ligand Complex Structure
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PDB6rfl Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Resolution2.76 Å
Binding residue
(original residue number in PDB)		Q125 K127 Y144 K187 K206 D231 K233 Y234 H252 N254 Y281
Binding residue
(residue number reindexed from 1)		Q124 K126 Y140 K170 K189 D214 K216 Y217 H235 N237 Y264
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6rfl, PDBe:6rfl, PDBj:6rfl
PDBsum6rfl
PubMed31835032
UniProtQ1PIU7

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