Structure of PDB 6oig Chain I Binding Site BS01

Receptor Information
>6oig Chain I (length=211) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARRPARCYRYQKNKPYPKSRYNRAVPDSKIRIYDLGKKKATVDEFPLCVH
LVSNELEQLSSEALEAARICANKYMTTVSGRDAFHLRVRVHPFHVLRINK
MQQGMRGAWGKPHGLAARVDIGQIIFSVRTKDSNKDVVVEGLRRARYKFP
GQQKIILSKKWGFTNLDRPEYLKKREAGEVKDDGAFVKFLSKKGSLENNI
REFPEYFAAQA
Ligand information
>6oig Chain 5 (length=3243) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagc
ggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaau
uuggagagggcaacuuuggggccguuccuugucuauguuccuuggaacag
gacgucauagagggugagaaucccguguggcgaggagugcgguucuuugu
aaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcauuugaucagacaugguguuuugua
uuucacuggccagcaucaguuuugguggcaggauaaauccauaggaaugu
agcuugccucgguaaguauuauagccugugggaauacugccagcugggac
ugaggacugcgacguaagucaaggaugcuggcauaaugguuauaugccgc
ccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuuggg
uguaaaacccauacgcguaaugaaagugaacguagguuggggccucgcaa
gaggugcacaaucgaccgauccugaugucuucggauggauuugaguaaga
gcauagcuguugggacccgaaagauggugaacuaugccugaauaggguga
agccagaggaaacucugguggaggcucguagcgguucugacgugcaaauc
gaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuagua
gcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguu
uuaugagguaaagcgaaugauuagagguuccggggucgaaaugaccuuga
ccuauucucaaacuuuaaauauguaagaaguccuuguuacuuaauugaac
guggacauuugaaugaagagcuuuuagugggccauuuuugguaagcagaa
cuggcgaugcgggaugaaccgaacguagaguuaaggugccggaauacacg
cucaucagacaccacaaaagguguuaguucaucuagacagccggacggug
gccauggaagucggaauccgcuaaggaguguguaacaacucaccggccga
augaacuagcccugaaaauggauggcgcucaagcguguuaccuauacucu
accgucaggguugauaugaugcccugacgaguaggcaggcguggagguca
gugacgaagccuagaccguaaggucgggucgaacggccucuagugcagau
cuuggugguaguagcaaauauucaaaugagaacuuugaagacugaagugg
ggaaagguuccacgucaacagcaguuggacguggguuagucgauccuaag
agauggggaagcuccguuucaaaggccugauuuuaugcaggccaccaucg
aaagggaauccgguuaagauuccggaaccuggauauggauucuucacggu
aacguaacugaauguggagacgucggcgcgagcccugggaggaguuaucu
uuucuucuuaacagcuuaucaccccggaauugguuuauccggagaugggg
ucuuauggcuggaagaggccagcaccuuugcuggcuccggugcgcuugug
acggcccgugaaaauccacaggaaggaauaguuuucaugccaggucguac
ugauaaccgcagcaggucuccaaggugaacagccucuaguugauagaaua
auguagauaagggaagucggcaaaauagauccguaacuucgggauaagga
uuggcucuaagggucggguagugagggucgcuugcuacaacgaucaacuu
agaacugguacggacaaggggaaucugacugucuaauuaaaacauagcau
ugcgauggucagaaagugauguugacgcaaugugauuucugcccagugcu
cugaaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggag
uaacuaugacucucuuaagguagccaaaugccucgucaucuaauuaguga
cgcgcaugaauggauuaacgagauucccacugucccuaucuacuaucuag
cgaaaccacagccaagggaacgggcuuggcagaaucagcggggaaagaag
acccuguugagcuugacucuaguuugacauugugaagagacauagagggu
guagaauaagugggagcuucggcgccagugaaauaccacuaccuuuauag
uuucuuuacuuauucaaugaagcggagcuggaauucauuuuccacguucu
agcauucaaggucccauucggggcugauccggguugaagacauugucagg
uggggaguuuggcuggggcggcacaucuguuaaacgauaacgcagauguc
cuaaggggggcucauggagaacagaaaucuccaguagaacaaaaggguaa
aagcccccuugauuuugauuuucagugugaauacaaaccaugaaagugug
gccuaucgauccuuuagucccucggaauuugaggcuagaggugccagaaa
aguuaccacagggauaacuggcuuguggcagucaagcguucauagcgaca
uugcuuuuugauucuucgaugucggcucuuccuaucauaccgaagcagaa
uucgguaagcguuggauuguucacccacuaauagggaacgugagcugggu
uuagaccgucgugagacagguuaguuuuacccuacugaugaauguuaccg
caauaguaauugaacuuaguacgagaggaacaguucauucggauaauugg
uuuuugcggcugucugaucaggcauugccgcgaagcuaccauccgcugga
uuauggcugaacgccucuaagucagaauccaugcuagaacgcggugauuu
cuuugcuccacacaauauagauggauacgaauaaggcguccuuguggcgu
cgcugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugg
gugcuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuug
uauacgacuuagauguacaacgggguauuguaagcaguagaguagccuug
uuguuacgaucugcugagauuaagccuuuguugucugauuugu
........................<<<<<<.....<......>......>
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.>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<
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<<<<........>>>><<<<<<...<.<<<<<.<<<<<<..<<....<<<
<.....>>>>....>>...<......>.......<<<<<..<<<<<....
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>>>>>>.>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<<....>>>>>>>.....>>>...<<<<.<<.<<........>>
>>>>>>....>>>>>>>>>...<<.......>>......>>>>>>.....
.>.>>..<<<<<<......<<<....>>><.<..<<<<<<<...<<<.<<
<<<<..<...<<<....<<.....<<<<...<.<<<<.....>>>>>..>
>>>.....>>..>>.>...>..>>>>...<<<<...<...........>.
..>>>>.....>>>>>.>>>>>>>...>>.<<<<.<<<<<.....>>>>>
.>>>>....<<<......>>>...<<<<<<<..<<<<(((.....<<<<<
<.....<<..........<<<.<<<<<<<<<......<..<<<<.<<...
.<<.........>>....>>.........<<......>>...>>>>..>.
.>>>>>>>>>>>>..........))).>>...>>>>>>.>>>>..>>>>>
>><<<<<<<<<.........>>>>>>>>>....>>>>>><..<<<<<<..
<<......<<<<.<<<<....>>>>>>>>...>>.>>>>>>...>.....
>>>>>><<.....<<.....<<<<<<.......>>>>>><<<<.....<<
<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<....
.....<<<....>>>..........<.............>..........
...>>...<<<<<........>>>>>))<<<<.<<<<<.<.....<<<..
..>>>........<<<<<...<<<<.<<<<<<<.<<<<<<<<<<..[[[.
.>>>>>>....<<<<<....<<<<<<....<<<.....>>>....>>>>>
>.....>>>>>.....<<<<<<<......>>>>>>>>>>>...>>>>>>>
.>>>>.........>>>>>...........>..>.>>>>>>>>.>>>..>
>.....<<......>>>>>>>.<<<.......>>>..>>>>..<<<<...
..<<<<<<<..................<<<<<...............>>>
>>...<<<<<<<<<<..........................>>>>..>>>
>>>...............<<<<<<<<<..<<<.........>>>...<<<
<<<.....<<<.....>>>.......>>>>>>....<<..<<<..<<<<<
<.<..........<<<<....>>>>........>>>>>..>>>>><<<<<
<.......>>>>>>........<...........<<<<.........>>>
>.....>.....>>....>>.>>>>>>>........>>>>>>>..>>>>>
>....>>....<<<<..........>>>>.....<<<<..<<<.<<....
..<<<<.<.<<<<..<<<<....<<<<<<...<<<<<<....<<......
.............................................>>...
..>>>>>>......<<<.....<<<<..<..<........>..>......
.........<<<<<<....>>>>>>..>>>>..>>>......>.>>>>>.
....>>>>...<<<.....>>>..<<<<<<...........>>>>>>..<
<...<<<<<<<...<<<<<<.......>>>>>>.....<<..[.((>>..
..>>>>>>>...<<<..<<<<.......>>>>..>>>.<<<....>>>.>
>))].......<<<<<<..<<<<.))).}.>>>>>>>>>>..........
>>>>...>>>>>....<..<<.<...<<<<<....<<.......>>....
>>>>>....>..>>.>.......<<<..<<<<<..<.<<<<<<<......
>>>>>>>...>.<<<.<.....>.>>>.....>>>>>......>>>....
...<<<<<<<....>>>.>>>>....>>..>>>.>>>>.....<<<<<<<
<..<<<....<<<<<<...............>>>>>>..<<<<<...<<<
<....<<<<<<<<<.]]]..>>>>..>>>>>..>.>>>..>>>>>.<<<<
...<<<<<...........>>>>>...>>>>..>>>....>>>>>>>>..
.....<<<<...<<<.<.....<<..........<<<<.........>>>
>......>>.......<<.<<....<.....<..<<<......>>>..>.
...>...>>.>>..............>>.>>...>>>>..<<<<<.....
................<<<<<.<<<.<<<.....<<<....<<<<<....
..>>>>>...>>>....>>>....>>>..>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6oig An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
A187 R188 R189 R192 C193 Y194 K198 N199 K200 P201 Y202 P203 R206 Y207 R209 Y219 D220 K224 K225 A252 R273 R275 V276 H277 F279 R283 N285 G299 M300 R301 G302 A303 W304 R339 Y342 K343 F344 P345 D378 G379 A380 F381 K383
Binding residue
(residue number reindexed from 1)
A1 R2 R3 R6 C7 Y8 K12 N13 K14 P15 Y16 P17 R20 Y21 R23 Y33 D34 K38 K39 A66 R87 R89 V90 H91 F93 R97 N99 G104 M105 R106 G107 A108 W109 R144 Y147 K148 F149 P150 D183 G184 A185 F186 K188
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6oig, PDBe:6oig, PDBj:6oig
PDBsum6oig
PubMed33219089
UniProtP41805|RL10_YEAST Large ribosomal subunit protein uL16 (Gene Name=RPL10)

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