Structure of PDB 6neq Chain I Binding Site BS01

Receptor Information
>6neq Chain I (length=311) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDVDRAITYLFPSGLFEK
RARPIMKHPEEIFPKQRAVQWGEDGRPFHFLFYTGKQSYYSLMHEAYGKV
LHAEERQDQIGSRWLIKEELEEMLVEKLSDQDYAQFIRLLERLSALPCDA
AEEEFVGRFRRTVTVQSKKHLIEPLQYDEQGMAFSTGQGKRKTANAEAVV
YGHGSGKIEINGVDYLLYFPVTQDREQLMFPFHFLDRLGKHDVTCTVSGG
GRSSQAGAIRLAMSRALCSFITEDEVEWMRQAGLLTTDPRVRERKKPGQE
GARRKFTWKKR
Ligand information
>6neq Chain A (length=952) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agguuuggucccagccuuccuguuaacucuuaauaaacuuacacaugcaa
gcaucuacaccccagugagaaugcccucuagguuauuaaaacuaagagga
gcuggcaucaagcacacacccuguagcucacgacgccuugcuuaaccaca
ccccacgggaaacagcagugacaaaaauuaagccauaaacgaaaguuuga
cuaaguuauauuaauuaggguugguaaaucucgugccagccaccgcgguc
auacgauuaacccaagcuaacaggaguacggcguaaaacguguuaaagca
ccauaccaaauaggguuaaauucuaacuaagcuguaaaaagccaugauua
aaauaaaaauaaaugacgaaagugacccuacaauagccgacgcacuauag
cuaagacccaaacugggauuagauaccccacuaugcuuagcccuaaacac
agauaauuacauaaacaaaauuauucgccagaguacuacuagcaacagcu
uaaaacucaaaggacuuggcggugcuuuauauccuucuagaggagccugu
ucuauaaucgauaaaccccgauaaaccucaccaauucuugcuaauacagu
cuauauaccgccaucuucagcaaacccuaaaaaggaaaaaaaguaagcgu
aauuaugauacauaaaaacguuaggucaagguguaaccuaugaaauggga
agaaaugggcuacauucucuacaccaagagaaucaagcacgaaaguuauu
augaaaccaauaaccaaaggaggauuuagcaguaaacuaagaauagagug
cuuaguugaauuaggccaugaagcacgcacacaccgcccgucacccuccu
caaauagauucagugcaucuaacccuauuuaaacgcacuagcuacaugag
aggagacaagucguaacaagguaagcauacuggaaagugugcuuggauaa
au
.<<.<<.{..[[>>.>>.<<<<<<<.<..<<<<<<<<..<.<<<.<<<..
<......>......<<......<<<<<<<.<<<<.....>>>>.>>>>>.
>>.<<<....<<...<<<...>>>..>>......>>>..<.....>.>>.
<<.....>>.....>>>>>>>.........<<....<<<<....>>>>..
>>...>>.>>>>>>...<<<<<<<<.....(((.....((.>>>))....
...)))..>>>>>..>.>>>>>>>.....<<<((.....<<<<....<..
..........<<<<<<.......<<<.<<.<<<......>>>..>>.>>>
...............<<....>>.>>>>>>......>....>>>>....<
<<<<<...<<...<<<<.........>>>>...>>>>>>>>.........
.<<<<<<.......))...>>>>>>.>>>.<<<.......<<<....>>>
.....>>>...]]..}<<<<<.<<<<<<<...<<..<<<<<..<<<<<<<
<.<.....<<........>>..........<<<.<<<...........<<
.<<<...<<<<<<......<<....<<<....>>>...........>>..
..<<<<.....>>>>......>.>>>...>>.>>>>>....>>>.>>>..
>..>>>>>>>>.....<<<<......>>>>..............<<<<<<
........>>>>>>..........>>>>>.....<<<<<<<.........
>>>>>>>......>>...>>>>>>>>>>.>>.......<<.<...<<<<<
<...<<.....<<<<<....<<......>>....>>>>>...>>.....>
>>>>>....>.>>.........<<<<<<<<<....>>>>>>>>>......
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6neq Structure of Human Mitochondrial Translation Initiation Factor 3 Bound to the Small Ribosomal Subunit.
Resolution3.32 Å
Binding residue
(original residue number in PDB)		F117 E118 Q216 R276 K277 P305 R337 S338 R375 R377 E378 R379 K380 K381 R388 R389 K390 T392 W393 K394 K395 R396
Binding residue
(residue number reindexed from 1)		F48 E49 Q131 R191 K192 P220 R252 S253 R290 R292 E293 R294 K295 K296 R303 R304 K305 T307 W308 K309 K310 R311
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6neq, PDBe:6neq, PDBj:6neq
PDBsum6neq
PubMed30677741
UniProtQ58DQ5|RT09_BOVIN Small ribosomal subunit protein uS9m (Gene Name=MRPS9)

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