Structure of PDB 5uk4 Chain I Binding Site BS01

Receptor Information
>5uk4 Chain I (length=415) Species: 11285 (Vesicular stomatitis Indiana virus strain San Juan) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDL
RGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDT
IGIFDLVSLKALDVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLM
DGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKK
HECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADE
MVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALL
LRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTP
DDSTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGL
REKTIGKYAKSEFDK
Ligand information
>5uk4 Chain x (length=45) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB5uk4 Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
Resolution3.204 Å
Binding residue
(original residue number in PDB)		R143 M149 Y152 K206 Y215 I218 V219 D224 A226 K286 S290 S291 V292 R312 N315 A316 R317 R408
Binding residue
(residue number reindexed from 1)		R136 M142 Y145 K199 Y208 I211 V212 D217 A219 K279 S283 S284 V285 R305 N308 A309 R310 R401
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0019083 viral transcription
GO:0039703 RNA replication
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5uk4, PDBe:5uk4, PDBj:5uk4
PDBsum5uk4
PubMed28396572
UniProtP03521|NCAP_VSIVA Nucleoprotein (Gene Name=N)

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