Structure of PDB 5nmp Chain I Binding Site BS01

Receptor Information

>5nmp Chain I (length=265) Species: 267608 (Ralstonia pseudosolanacearum GMI1000) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AMATSTTPTILPALAAGLARGNIRVVDLTQTLSPSFPTLQLPSQFGQVQP
FKIERISHYDASGPAWYWNNFSCGEHTGTHFDAPAHWITGRDYPGNSVDT
IAPENFVAPAVVIDASAQVRENEDWLLTVDFLQAWEQRHGRIPAGAWVLF
RTDWSLRVGDAAAFLNIREDGAHTPGPTQEAVEWLIGERNVHGFGVETIN
TDAGQSYAWPLAYPCHTLMHGANRYGLQCLKNLDQLPPRGAFILAAPLKI
EGGSGSPLRVLALVE

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

5nmp Chain I Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5nmp A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase.
Resolution	2.65 Å
Binding residue (original residue number in PDB)	H74 H78 D80 Q226
Binding residue (residue number reindexed from 1)	H76 H80 D82 Q228
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004061	arylformamidase activity
GO:0046872	metal ion binding

	Biological Process
GO:0019441	tryptophan catabolic process to kynurenine

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Molecular Function

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Biological Process

External links

PDB	RCSB:5nmp, PDBe:5nmp, PDBj:5nmp
PDBsum	5nmp
PubMed	30166577
UniProt	Q8XYC3

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