Structure of PDB 5jcz Chain I Binding Site BS01

Receptor Information
>5jcz Chain I (length=147) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATKAQIWDTAGQ
ERAITSAYYRGAGALLVYDIAKHLTYENVERWLKELRDHADSVIMLVGNK
SDRHLRAVPTEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5jcz Chain I Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jcz Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.
Resolution2.056 Å
Binding residue
(original residue number in PDB)		S25 T43
Binding residue
(residue number reindexed from 1)		S15 T33
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:5jcz, PDBe:5jcz, PDBj:5jcz
PDBsum5jcz
PubMed27623148
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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