Structure of PDB 5akf Chain I Binding Site BS01

Receptor Information
>5akf Chain I (length=175) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITAKSENLIKQHIAP
LMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMR
EQIAFIKGLYVAEGDMTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLD
DHRHGVYVLNISLRDRIKFVHTILS
Ligand information
Receptor-Ligand Complex Structure
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PDB5akf Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		D21 T41 K43 T76 R124 T150 H152 D154 R157 S166 L167
Binding residue
(residue number reindexed from 1)		D17 T37 K39 T72 R120 T146 H148 D150 R153 S162 L163
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0016539 intein-mediated protein splicing

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Molecular Function
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Biological Process
External links
PDB RCSB:5akf, PDBe:5akf, PDBj:5akf
PDBsum5akf
PubMed26045557
UniProtP21505|DMO1_DESMO Homing endonuclease I-DmoI

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