Structure of PDB 4yhh Chain I Binding Site BS01 |
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| >4yhh Chain A (length=1507)
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guuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaag
acaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcgga
cgggugaguaacgcgugggugaccuacccggaagagggggacaacccggg
gaaacucgggcuaaucccccauguggacccgccccuugggguguguccaa
agggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggug
ggguaauggcccaccaaggcgacgacggguagccggucugagaggauggc
cggccacaggggcacugagacacgggccccacuccuacgggaggcagcag
uuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuugg
aggaagaagcccuucgggguguaaacuccugaacccgggacgaaaccccc
gacgaggggacugacgguaccgggguaauagcgccggccaacuccgugcc
agcagccgcgguaauacggagggcgcgagcguuacccggauucacugggc
guaaagggcguguaggcggccuggggcgucccaugugaaagaccacggcu
caaccgugggggagcgugggauacgcucaggcuagacggugggagagggu
gguggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgc
cgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaag
cguggggagcaaaccggauuagauacccggguaguccacgcccuaaacga
ugcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagc
gcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacg
ggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaa
gaaccuuaccaggccuugacaugcuagggaacccgggugaaagccugggg
ugccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcu
cgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccg
uuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaaag
cgggaggaaggaggggacgacgucuggucagcauggcccuuacggccugg
gcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacg
gggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacc
cgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcg
gugaauacguucccgggccuuguacacaccgcccgucacgccaugggagc
gggcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagg
gcccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcg
gcuggau |
......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<
<<.<<<..<<<..<<.<<<<<<<<<.......>>>>>>>>>.>>>>>...
...<<..<....<<<<<<<<..<<...<<<<<<<.<<<<.....<<<<<<
....>>>>>>......>>>>....<<<<.<<<<<....>>>>>.>>>>..
.<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>>>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>>
>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>....<<<<<........<<<<
.....>>>>..........>>>>>......<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<
((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<..
...>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<
<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>.>.....
.....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<
<<<<<...<<...<<<<.........>>>>...>>>>>>>>.........
.<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>
>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<
.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>..
........<<<<<<<.......<<<<<<<..<<<<<<<....>>>>>>>.
..<<<<....>>>>..>>>>>>>..<<<.<<<..<<<<<<.......<<<
<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<
<<<...<<<..<<<.....>>>>>>....>>>>>>.....<<<<<....>
>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>>
...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>
>>..>>....>>>.....>>>>>>>......<....<<<<<<<.......
.>>>>>>>....>.....>>>>>>....<<<<<<<..........>>>>>
>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<...<<
<<<<<<<<<<<...<.<<<<....<<<<..>>>>.>>>>.>..>>>>>>>
>>>>>>...>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>
>>>.... |
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| PDB | 4yhh Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome. |
| Resolution | 3.417 Å |
Binding residue
(original residue number in PDB) | Y5 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 G39 L40 R42 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 R111 K112 K113 Y114 G115 H117 K118 R120 R121 Q124 Y125 K127 R128 |
Binding residue
(residue number reindexed from 1) | Y4 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 G38 L39 R41 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 R110 K111 K112 Y113 G114 H116 K117 R119 R120 Q123 Y124 K126 R127 |
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| Enzyme Commision number |
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