Structure of PDB 4v94 Chain I Binding Site BS01

Receptor Information
>4v94 Chain I (length=539) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLFNNSRSDTLFLGGEKISGDDIRNQNVLATMAVANVVKSSLGPVGLDKM
LVDDIGDFTVTNDGATILSLLDVQHPAGKILVELAQQQDREIGDGTTSVV
IIASELLKRANELVKNKIHPTTIITGFRVALREAIRFINEVLSTSETLIN
IAKTSMSSKIIGADSDFFSNMVVDALLAVKTQNSKGEIKYPVKAVNVLKA
HGKSATESLLVPGYALNCTVASQAMPKRIAGGNVKIACLDLNLQKARMAM
GVQINIDDPEQLEQIRKREAGIVLERVKKIIDAGAQVVLTTKGIDDLCLK
EFVEAKIMGVRRCKKEDLRRIARATGATLVSSMSNLEGEETFESSYLGLC
DEVVQAKFSDDECILIKGTSKHSSSSIILRGANDYSLDEMERSLHDSLSV
VKRTLESGNVVPGGGCVEAALNIYLDNFATTVGSREQLAIAEFAAALLII
PKTLAVNAAKDSSELVAKLRSYHAASQMAKPEDRSYRNYGLDLIRGKIVD
EIHAGVLEPTISKVKSLKSALEACVAILRIDTMITVDPE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4v94 Chain I Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4v94 The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		D96 K167
Binding residue
(residue number reindexed from 1)		D94 K159
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D65 T98 T99 D404
Catalytic site (residue number reindexed from 1) D63 T96 T97 D396
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0051086 chaperone mediated protein folding independent of cofactor
Cellular Component
GO:0005737 cytoplasm
GO:0005832 chaperonin-containing T-complex
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v94, PDBe:4v94, PDBj:4v94
PDBsum4v94
PubMed22503819
UniProtP12612|TCPA_YEAST T-complex protein 1 subunit alpha (Gene Name=TCP1)

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