Structure of PDB 4tvx Chain I Binding Site BS01

Receptor Information
>4tvx Chain I (length=493) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLV
CIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQ
TKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQA
NQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNE
SHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSC
CGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTT
SAPSWTQISRVVVDKIIQNNGNRVAAVVNQFRNIAPQSPLELIMGGYRNN
QASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGF
KNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDK
LHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQ
Ligand information
>4tvx Chain L (length=61) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaaaccgacgguauuguucagauccuggcuugccaacaggaguuccccg
cgccagcgggg
.............................................<<<<<
<....>>>>>>
Receptor-Ligand Complex Structure
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PDB4tvx Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli.
Resolution3.24 Å
Binding residue
(original residue number in PDB)		F129 V130
Binding residue
(residue number reindexed from 1)		F127 V128
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tvx, PDBe:4tvx, PDBj:4tvx
PDBsum4tvx
PubMed25103409
UniProtQ46901|CSE1_ECOLI CRISPR system Cascade subunit CasA (Gene Name=casA)

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