Structure of PDB 4gko Chain I Binding Site BS01

Receptor Information
>4gko Chain I (length=134) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQ
DFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGE
DCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4gko Chain I Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4gko Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		E249 E257 N269 D270
Binding residue
(residue number reindexed from 1)		E92 E100 N112 D113
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4gko, PDBe:4gko, PDBj:4gko
PDBsum4gko
PubMed23775083
UniProtP06734|FCER2_HUMAN Low affinity immunoglobulin epsilon Fc receptor (Gene Name=FCER2)

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