Structure of PDB 4f2n Chain I Binding Site BS01
Receptor Information
>4f2n Chain I (length=209) Species:
5664
(Leishmania major) [
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CYHTLPHLRYPAELPTLGFNYKDGIQPVMSPRQLELHYSKHHSAYVDKLN
TLGKGYEGKTIEEIILATTGINESKVMFNQAAQHFNHSFFWKCLSPGGKP
MPKTLENAIAKQFGSVDDFMVSFQQAGVNNFGSGWTWLCVDPQTKELLID
STSNAGCPLTSGLRPIFTADVWEHAYYKDFENRRADYLKELWQIVDWEFV
CHMYERATK
Ligand information
Ligand ID
FE2
InChI
InChI=1S/Fe/q+2
InChIKey
CWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Fe+2]
CACTVS 3.341
[Fe++]
Formula
Fe
Name
FE (II) ION
ChEMBL
DrugBank
DB14510
ZINC
PDB chain
4f2n Chain I Residue 300 [
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Receptor-Ligand Complex Structure
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PDB
4f2n
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.
Resolution
1.85 Å
Binding residue
(original residue number in PDB)
H58 H108 D191 H195
Binding residue
(residue number reindexed from 1)
H37 H87 D170 H174
Annotation score
1
Enzymatic activity
Enzyme Commision number
1.15.1.1
: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0004784
superoxide dismutase activity
GO:0016491
oxidoreductase activity
GO:0046872
metal ion binding
Biological Process
GO:0006801
superoxide metabolic process
GO:0019430
removal of superoxide radicals
Cellular Component
GO:0005739
mitochondrion
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4f2n
,
PDBe:4f2n
,
PDBj:4f2n
PDBsum
4f2n
PubMed
25961325
UniProt
Q4QIE0
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