Structure of PDB 4b3m Chain I Binding Site BS01 |
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>4b3m Chain A (length=1512)
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uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca accgugggggagcgugggauacgcucaggcuagacggugggagagggugg uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug ccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucg ugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguu aguugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcg ggaggaaggaggggacgacgucuggucagcauggcccuuacggccugggc gacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacggg gagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccg accccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggu gaauacguucccgggccuuguacacaccgcccgucacgccaugggagcgg gcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggc ccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggc uggauccuuucu |
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<< .<<<..<<<..<<.<<<<<<<<<<.....>>>>>>>>>>.>>>>>..... .<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<... ...>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..< <<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<< .......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>> >>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>> >........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<< ......<<<<....>>>>.....>>>>....<<<<<......<.<<<<.. ...>>>>..>.......>>>>>......<<<<<(((...<<<<<.....< <.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(( .....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.... .>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<< <....<<<<<<<.<..<<<......>>>.....>.>>>>>>>........ ...<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<< <<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........< <<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>> >>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.< <<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.... ......<<<<<<<......<<<<<.<<..<<<<<<<....>>>>>>>... <<<<....>>>>...>>>>>>>.<<<.<<<..<<<<<<<......<<<<< <<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<< <<...<...<<<.....>>>>.....>>>>>>>.....<<<<<....>>> >>........>>>>.......>.>>>...>>>>>>>>>...>>>>>>>.. .>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>> ..>>....>>>.....>>>>>>>...........<<<<<<<........> >>>>>>..........>>>>>>....<<<<<<<..........>>>>>>> ......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<< <<<<<<<<<...<.<<<<....<<<<..>>>>.>>>>.>..>>>>>>>>> >>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>> >........... |
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PDB | 4b3m 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics |
Resolution | 2.9 Å |
Binding residue (original residue number in PDB) | Q2 Y4 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 R127 |
Binding residue (residue number reindexed from 1) | Q2 Y4 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 R127 |
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Enzyme Commision number |
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